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Table 3 Management and prognosis of KFD patients

From: Macrophage activation syndrome in children with Kikuchi-Fujimoto disease

 

Without MAS (n = 43)

With MAS (n = 15)

p-value

Treatment

 IVIG

7 (16.3%)

3(20.0%)

 > 0.9999

 Glucocorticoids

15 (34.9%)

12 (80.0%)

0.003

 Cyclosporine

0 (0.0%)

1 (6.7%)

0.26

 VP-16

0 (0.0%)

1 (6.7%)

0.26

 Tofacitinib

0 (0.0%)

1 (6.7%)

0.26

 Antibiotics

19 (66.7%)

10 (66.7%)

0.23

Hosptial durations (days)

11 (9–13)

11 (10–21)

0.41

Recurrence of KFD

4 (9.3%)

5 (33.3%)

0.04

Progression to autoimmune diseases

2 (4.7%)

1 (6.7%)

 > 0.9999

  1. KFD Kikuchi-Fujimoto disease, MAS macrophage activation syndrome, IVIG intravenous immunogloblin; VP16, etoposide; GCs, glucocortic