Table 2 Laboratory findings of KFD patients
From: Macrophage activation syndrome in children with Kikuchi-Fujimoto disease
Without MAS (n = 43) | With MAS (n = 15) | p-value | |
|---|---|---|---|
Laboratory variables | |||
WBC count (/μL) | 3940 (2990–4620) | 2330 (1560–4200) | 0.02 |
Hemoglobin (g/dL) | 117 (109–127) | 105 (97–129) | 0.26 |
Neutrophil count (/μL) | 1680 (1250–2500) | 1230 (550–2900) | 0.25 |
Lymophocyte count (/μL) | 1540 (1280–1940) | 1070 (800–1220) | < 0.0001 |
Platelet count (× 106/μL) | 213 (180–274) | 161 (117–203) | 0.002 |
AST (IU/L) | 34.0 (25.0–46.0) | 73.0 (49.0–96.0) | 0.09 |
ALT (IU/L) | 18.0 (11.0–32.0) | 29.0 (13.0–55.0) | 0.22 |
Albumin (g/L) | 38.9 (37.1–40.2) | 34.7 (32.6–38.5) | 0.01 |
Ferritin (ng/mL) | 207.6 (119.9–350.4) | 1756.0 (785.2–3118.0) | 0.11 |
Triglyceride (mg/dl) | 1.2 (1.0–1.5) | 0.96 (0.85–1.5) | 0.77 |
Fibrinogen (mg/dL) | 3.8 (3.4–4.3) | 3.5 (2.6–4.5) | 0.16 |
CRP (mg/L) | 5.0 (2.1–11.9) | 8.5 (1.3–24.3) | 0.18 |
ESR (mm/h) | 35.0 (24.0–47.0) | 43.0 (32.0–50.0) | 0.4 |
LDH (IU/mL) | 380.0 (284.0–458.0) | 857.0 (762.0–1005.0) | < 0.0001 |
Hemophagocytosis by bone marrow biopsy | 16 (61.5, n = 26) | 10 (71.4, n = 14) | 0.73 |
Positive autobodies | 9 (20.9) | 2 (13.3) | 0.71 |