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Fig. 3 | Pediatric Rheumatology

Fig. 3

From: Profiling the peripheral immune response to ex vivo TNF stimulation in untreated juvenile idiopathic arthritis using single cell RNA sequencing

Fig. 3

Variance components of gene expression. Bar plots show the average proportion of variance explained across all expressed genes by Stimulus, Status, Interaction, and Individual donor terms, assessed using variancePartition software, for the 9 indicated cell types. Colors represent three replicates of 5-cell and 20-cell pseudo-cell pooling assignments in scPool, clearly showing high repeatability and increased variance explained as more cells are pooled. Individual has the largest overall effect, followed by TNF stimulus

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Pediatric Rheumatology

ISSN: 1546-0096