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Fig. 2 | Pediatric Rheumatology

Fig. 2

From: Profiling the peripheral immune response to ex vivo TNF stimulation in untreated juvenile idiopathic arthritis using single cell RNA sequencing

Fig. 2

Notable influences of Stimulus and Status on Cell Proportions. Each plot shows the proportion of the indicated cell type in the total cell population for each sample, ordered in pairs of Null (unstimulated) and TNF (stimulated) with the two healthy controls on the left and six JIA to the right. The prefixes C and J in sample names represent Control and JIA respectively. Significant effects by mixed novel ANOVA of the proportions are indicated (non-significant otherwise), including Stimulus for naïve B-cells, CD8 + T-cells, and NK56 cells; JIA Status for Memory CD8 + T-cells; and the Stimulus × Status interaction for Dendritic and NK56 cells. These effects can be seen in the slopes of the lines connecting each pair of samples

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Pediatric Rheumatology

ISSN: 1546-0096