Haptoglobin in Juvenile Idiopathic Arthritis

Table 4 Spearman rank correlation analysis of liver derived APP concentrations and JADAS27 scores in juvenile idiopathic arthritis. ESR is included separately because it is only one component of JADAS27 scoring, which allows for comparison to Hp and other APPs.

	Hp(IT)	CRP	SAA	Albumin	Hp(IT)/Alb	JADAS27	ESR
Hp(WB)	0.489	0.442	0.165	-0.358	0.501	0.308	0.436
	< 0.001	< 0.001	0.2	< 0.001	< 0.001	< 0.001	< 0.001
	132	136	58	132	132	136	135
Hp(IT)		0.716	0.6	-0.532	0.994	0.592	0.613
		< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001
		132	54	132	132	132	132
CRP			0.814	-0.502	0.726	0.472	0.662
			< 0.001	< 0.001	< 0.001	< 0.001	< 0.001
			58	132	132	136	135
SAA				-0.28	0.594	0.496	0.629
				0.04	< 0.001	< 0.001	< 0.001
				54	54	58	57
Albumin					-0.601	-0.443	-0.525
					< 0.001	< 0.001	< 0.001
					132	132	132
Hp(IT)/Alb						0.608	0.626
						< 0.001	< 0.001
						132	132
JADAS27							0.485
							< 0.001
							139

Top numbers are Spearman rank order correlation coefficients; Middle numbers are p values; Bottom numbers are sample sizes and reflect all data available to make that paired comparison. APP acute phase proteins, JADAS27 Juvenile Arthritis Disease Activity Score (0–57), CRP C-reactive protein, ESR erythrocyte sedimentation rate, Hp haptoglobin, Hp(WB) haptoglobin by Western blot, Hp(IT) haptoglobin by immunoturbidimetry, SAA serum amyloid A

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