Fig. 4

Association between JIA PRS, and A continuous and B dichotomous cardiovascular phenotypes at age 24 years. Estimates are presented as unadjusted (grey) and adjusted for 10 principal components and sex (black). Apo-AI, apolipoprotein AI; Apo-B, apolipoprotein B; BMI, body mass index; BP, blood pressure; cIMT, carotid intima media thickness; FMI, fat mass index; HDL, high density lipoprotein cholesterol; HOMA2_IR, Homeostasis Model Assessment 2 insulin resistance index; hsCRP, high sensitivity C-reactive protein; IDH, isolated diastolic hypertension; JIA, juvenile idiopathic arthritis; LDL, low density lipoprotein cholesterol; LVMI, left ventricular mass index; PRS, polygenic risk score; SD standard deviation