Patient No. | 1 | 2 | 3 |
---|---|---|---|
Age, yrs./sex | 14/M | 14/M | 15/M |
Disease duration, months | 48 | 0 | 3 |
Lesions revealed by whole-body bone scintigraphy | Right mandible | Bilateral sternoclavicular joints, hip joints and sacroiliac joints | Sternum, T8, T10, L4, L5, left hip joint, left femur, right ischium |
Dermatological manifestation | Nodules, drainage incisions and scars on cheeks, lower jaw, upper arms and chest | Nodules, drainage incisions, sinus tracks and scars on forehead, cheeks, upper back and buttocks | Nodules, drainage incisions and scars on forehead, cheeks, back and chest |
Prior treatments | NSAIDs, antibiotics, TNFi, | NSAIDs, TGP | NSAIDs, minocycline, SASP, TNFi, BPs |
TNFi therapy | Etanercept (50 mg, qw) | Etanercept (50 mg, qw) | Adalimumab (40 mg, q2w) |
Clinical scores | |||
 Pain VAS | 0 | 2 | 2 |
 BASDAI | 0.8 | 0.8 | 1.0 |
 BASFI | 0.3 | 0.5 | 5.1 |
 ASDAS | 1.2 | 3.1 | 3.4 |
 HAQ-S | 0 | 0.125 | 3.125 |
 DLQI | 6 | 2 | 6 |
Laboratory findings | |||
 ESR, mm/h | 5 | 26 | 54 |
 CRP, g/L | 5.03 | 30.7 | 32.7 |