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Table 1 (abstract P037). Clinical characteristics among biologic switchers and non-switchers in juvenile idiopathic arthritis (JIA)

From: Proceedings of the 28th European Paediatric Rheumatology Congress (PReS 2022)

 

Switchers

Non- switchers

p-value

N

74

126

 

Male

17 (23)

40 (32)

0.185

Female

57 (77)

86 (68)

Subcategory, n (%)

 - Persistent Oligo

10 (13.5)

16 (13)

0.549

 - Extended Oligo

27 (36.5)

34 (27)

 

 - RF+ Polyarticular JIA

2 (3)

6 (5)

 

 - RF- Polyarticular JIA

23 (31)

36 (29)

 

 - Psoriatic

4 (5)

9 (7)

 

 - ERA

5 (7)

19 (15)

ERA: 0.08

 - Undifferentiated

3 (4)

6 (5)

 

1st biologic, n (%)

 ETN

49 (66)

50 (40)

Enbrel vs Benepali:

 Enbrel

36 (73)

35 (70)

0.911

 Benepali

13 (27)

12 (24)

 

 Erelzi

0

3 (6)

ETN vs ADA:

<0.001

ADA

15 (20)

61 (48)

 

GOL

4 (6)

14 (11)

 

IFX

6 (8)

1 (1)

 

Disease duration (years)

7.3 (4.7-10.6)

5.4 (3.5-9.0)

0.017

Active joints at start of 1st biologic

2 (1-4)

2 (1-4)

0.987

Cumulative joints at start of 1st biologic

3 (1-8)

6 (4.25-10)

<0.001

DMARD before 1st biologic

69 (93)

107 (85)

0.042

DMARD plus 1st biologic

55 (74)

102 (81)

0.128

  1. Data are expressed as medians with interquartile range (IQR) or as number of patients with % in parentheses. RF: rheumatoid factor; ERA: enthesitis related arthritis; ETN: etanercept; ADA: adalimumab; GOL: golimumab; IFX: infliximab