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Table 3 Correlation analysis of serum RANKL level and other indexes in children with SLE(n or mean ± SD

From: Bone remodeling serum markers in children with systemic lupus erythematosus

 

SLE group(n = 40)

R value

P value

Age(years)

10.75 ± 2.56

-0.105

0.519

Duration of SLE(Months)

14.95 ± 4.94

0.593

 < 0.0001*

Weight(kg)

42.33 ± 9.68

-0.279

0.081

Height(cm)

131.33 ± 13.92

-0.141

0.385

BMI(kg/m2)

24.64 ± 4.88

-0.176

0.278

Accumulated dose of GC (mg/kg)

292.33 ± 67.93

0.727

 < 0.0001*

RANKL(pg/ml)

9.82 ± 7.20

-

-

OPG(pg/ml)

156.34 ± 57.33

-0.601/-0.66b

 < 0.0001*

25(OH)vitD3(mmol/L)

43.66 ± 31.27

-0.469/-0.508b

0.002*/-0.001*

  1. SLE Systemic lupus erythematosus, RANKL Receptor activator of nuclear factor-κB ligand, OPG Osteoprotegerin, BMI Body Mass Index, GC Glucocorticoid
  2. *P < 0.05, the difference was statistically significant
  3. b The correlation with accumulated dose of GC