Myeloid-related protein 8/14 in plasma and serum in patients with new-onset juvenile idiopathic arthritis in real-world setting in a single center

Table 2 Linear regression analyzes for the contribution of the laboratory parameters on PGA in VAS (0-100 mm) in all the 87 juvenile idiopathic arthritis patients

Analysis	Laboratory parameters	Crude β	95% CI	P-value
Univariate analysis
	C-reactive protein mg/l	0.34	0.23, 0.46	< 0.001
	ESR mm/h	0.36	0.20, 0.52	< 0.001
	Leucocytes E9/l	1.34	0.01, 2.66	0.048
	Neutrophils E9/l	1.85	−0.27, 3.98	0.09
	MRP8/14 in plasma ng/ml	0.07	0.06, 0.09	< 0.001
	MRP8/14 in serum ng/ml	0.06	0.03, 0.09	< 0.001
Multivariate analysis with MRP8/14 in plasma		Adjusted β
	C-reactive protein mg/l	0.16	−0.02, 0.34	0.08
	ESR mm/h	−0.09	−0.34, 0.15	0.46
	Leucocytes E9/l	0.01	−2.12, 2.13	0.99
	Neutrophils E9/l	−0.31	−3.65, 3.03	0.85
	MRP8/14 in plasma ng/ml	0.07	0.03, 0.10	< 0.001
Multivariate analysis with MRP8/14 in serum		Adjusted β
	C-reactive protein mg/L	0.29	0.11, 0.47	0.002
	ESR mm/h	0.05	−0.21, 0.31	0.69
	Leucocytes E9/L	0.59	−1.56, 2.75	0.58
	Neutrophils E9/L	−0.75	−3.9, 2.42	0.64
	MRP8/14 in serum ng/mL	0.01	−0.03, 0.05	0.56

β regression coefficient, CI confidence interval, ESR Erythrocyte sedimentation rate, MRP8/14 Myeloid-related protein 8/14, PGA Physician’s global assessment of disease activity, VAS visual analog scale

ISSN: 1546-0096