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Table 4 Treatment effects

From: Changes over time in inflammatory and structural lesions at the sacroiliac joint in children with spondyloarthritis exposed and unexposed to tumor necrosis factor inhibitor

 

N

Average treatment effect (95% CI)

p-value

SIS

 All

42

−7.85 (− 12.22, −3.49)

0.00

 Baseline SIS≥2*

21

− 14.50 (− 21.62, − 7.37)

0.00

 Baseline SIS< 2

21

− 1.27 (− 4.37, 1.83)

0.42

SSS

 Erosion

18

0.72 (−1.88, 3.31)

0.588

 Sclerosis

18

−0.18 (− 0.93, 0.56)

0.628

  1. Legend. Average treatment effects from TNFi use, adjusting for baseline SIS or SSS lesions scores as appropriate. Exposure defined as ≥90 days of TNFi use. *SPARCC SIS score ≥ 2 is used as a surrogate for MRI-sacroiliitis positive in clinical trials [23]
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Pediatric Rheumatology

ISSN: 1546-0096