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Table 3 Subjects without TNFi exposure who met SIS MCID

From: Changes over time in inflammatory and structural lesions at the sacroiliac joint in children with spondyloarthritis exposed and unexposed to tumor necrosis factor inhibitor

Subject Sex Time between MRI scans (months) Pain change score Baseline SIS Follow-up SIS Baseline Erosion Follow-up Erosion NSAIDs cDMARD TNFi exposure (days)
1 M 8.5 34.7 7 11 4.3 None None 0
2 M 33.8 −4 14.3 0 5.3 5.7 Yes MTX 0
3 M 22.1 3 0 0 0 Yes SSZ 0
4 M 5.8 13.3 4 5 9 Yes None 0
5 M 36.0 30.7 16 0 0 Yes None 0
6 F 35.7 24.7 4.5 0 4.7 Yes SSZ 0
7 M 7.5 −1 10.3 0 0 0 Yes None 0
8 F 2.9 −1 28.5 0 10 13 Yes MTX 67
  1. Legend. M = Male, F=Female, NSAIDs = nonsteroidal anti-inflammatory drugs, csDMARD = conventional disease modifying anti-rheumatic drug; MTX = methotrexate, SSZ = sulfasalazine