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Table 3 Subjects without TNFi exposure who met SIS MCID

From: Changes over time in inflammatory and structural lesions at the sacroiliac joint in children with spondyloarthritis exposed and unexposed to tumor necrosis factor inhibitor

Subject

Sex

Time between MRI scans (months)

Pain change score

Baseline SIS

Follow-up SIS

Baseline Erosion

Follow-up Erosion

NSAIDs

cDMARD

TNFi exposure (days)

1

M

8.5

–

34.7

7

11

4.3

None

None

0

2

M

33.8

−4

14.3

0

5.3

5.7

Yes

MTX

0

3

M

22.1

–

3

0

0

0

Yes

SSZ

0

4

M

5.8

–

13.3

4

5

9

Yes

None

0

5

M

36.0

–

30.7

16

0

0

Yes

None

0

6

F

35.7

–

24.7

4.5

0

4.7

Yes

SSZ

0

7

M

7.5

−1

10.3

0

0

0

Yes

None

0

8

F

2.9

−1

28.5

0

10

13

Yes

MTX

67

  1. Legend. M = Male, F=Female, NSAIDs = nonsteroidal anti-inflammatory drugs, csDMARD = conventional disease modifying anti-rheumatic drug; MTX = methotrexate, SSZ = sulfasalazine