Economic impact of Juvenile Idiopathic Arthritis: a systematic review

Table 2 Detailed direct health care cost description from eligible studies

Article	Original currency	Rheumatology medical appointments^a	Other doctors medical appointments^a	Medications^a	Hospitalization^a	Physiotherapy^a	Devices^a	Transportation^a
Angelis, 2016 [7]	EUR 2012	5,925		9,475	1,488		162	106
Bernatsky, 2007 [23]	CAD 2005	383	447	1,435	406	99	53
Ens, 2013 [4]	CAD 2009	345	123	189		1	51	37
Haapasaari, 2004 [26]^bc	USD 2000			5,782		2,310
Hughes, 2018 [14]^cd	GBP 2016	69	30			17
Yucel, 2012 [27]	EUR 2009	94		5,794	46	35	21	322
Marshall, 2019 [28]^e	USD 2016	1,727	8,666	6,626	2,251
Minden, 2009 [18]	EUR 2018			2,247	1,577	285		150
Prince, 2011 [19]^c	EUR 2005			13,355
Shenoi, 2018 [20]^f	USD 2016							1,014
Thornton, 2008 [22]	GBP 2008	1,731	898	408
Khatun, 2021 [15]	INR 2018	1.90		99	51			34
Kip, 2020 [16]	EUR 2019			2,436
Thakral, 2020 [21]^g	USD 2014	348		3,161

CAD Canada dollar, USD United States dollar, EUR Euro, GBP Great Britain pound, INR Indian rupee
^aAdjusted to inflation and converted to US Dollar. Based on exchange rate on December 31, 2019
^bThis article only reports quarterly cost
^cCosts after biologic therapy started
^dThis article reports costs on an 18-months period
^eOnly JIA related Costs
^fOnly Systemic JIA
^gOnly Oligoarticular JIA

ISSN: 1546-0096