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Table 4 Diagnostic specificity and sensitivity according to ROC-optimized decision limits for ALBI, ALB, and TBil in predicting initial IVIG resistance among patients with KD

From: Predictive value of Albumin-Bilirubin grade for intravenous immunoglobulin resistance in a large cohort of patients with Kawasaki disease: a prospective study

 

Estimated specificity at fixed sensitivity (n = 823)

Estimated sensitivity at fixed specificity (n = 823)

ALBI

Sensitivity(%)

Specificity(%)

Cut-off point

n

Specificity(%)

Sensitivity(%)

Cut-off point

n

 

99.0

7.9

-3.29

767

99.0

10.4

-1.58

20

 

97.5

13.3

-3.18

727

97.5

13.9

-1.77

35

 

95.0

17.2

-3.12

698

95.0

26.1

-1.97

66

 

90.0

23.6

-3.02

648

90.0

40.9

-2.15

120

ALB

        
 

99.0

8.5

43.8

753

99.0

4.4

26.0

12

 

97.5

12.6

42.9

713

97.5

15.9

28.8

35

 

95.0

16.6

41.9

661

95.0

25.2

30.4

64

 

90.0

20.1

41.9

661

90.0

30.7

31.8

93

TBil

        
 

99.0

1.5

1.91

816

99.0

6.9

47.9

16

 

97.5

2.3

1.93

816

97.5

17.4

30.3

38

 

95.0

3.5

1.96

816

95.0

24.2

18.6

65

 

90.0

11.7

2.94

771

90.0

29.5

12.9

106

  1. Abbreviations: ALBI albumin-bilirubin index; ALB albumin; TBil total bilirubin; IVIG intravenous immunoglobulin; KD Kawasaki disease