From: Proceedings of the 27th European Paediatric Rheumatology Congress (PReS 2021)
 | Patient 1 | Patient 2 |
---|---|---|
RF/anti – CCP / ANA | (-) / (-) / (-) | (+) /(+) /(+) |
Rheumatoid nodules / morning stiffness | (-) / (+) | (+)/ (+) |
Anti- TNF a | Etanercept (4 months) Adalinumab (2 years) | Adalinumab (9 years) |
Neurological symptoms | right facial palsy Romberg right | Left optic neuritis |
 Anti- MOG / Anti- AQP4 | (-) / (-) | (-) / (-) |
 Oligoclonal bands | type 3 | type 2 |
 MRI lesions of the brain – focal high intensity white matter lesions | in cerebral hemispheres & brain stem | in optic nerves & next to the lateral ventricles |
 MRI lesions of the spinal cord without enhancement | at the cervical level C2 and thoracic level T6, T11- T12 | at the cervical level C5 |
Autoimmune medical history | ENA (-) | ENA (-) Anti- TPO (+) Anti-TG (+) |
Family medical history of RA | paternal aunt | grand mother |