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Table 1 (abstract P13). Expression of phenotypic markers on oJIA SF and PB B cells

From: Proceedings of the 27th European Paediatric Rheumatology Congress (PReS 2021)

Phenotypic marker

Brief description

Expression on oJIA synovial fluid B cells (n=18)

(median, interquartile range)

Expression on oJIA peripheral blood B cells (n=17)

(median, interquartile range)

Result of Mann-Whitney U test

CD86

Activation marker involved in antigen presentation

33.4% (21.7%-46.3%) positive expression

10.0% (6.9%-14.2%) positive expression

p<0.0001

U=3

HLA-DR

Activation marker involved in antigen presentation

4096 (3347-4927) median fluorescent intensity

1874 (1738-2074) median fluorescent intensity

p<0.0001

U=16

CD11c

Activation marker

59.3% (46.0%-68.9%) positive expression

20.0% (15.1%-25.2%) positive expression

p<0.0001

U=6

FcRL4

Atypical marker expressed on pro-arthritogenic B cells in rheumatoid arthritis (1)

20.0% (13.7%-46.3%) positive expression

13.4% (10.3%-18.0%) positive expression

p=0.0240

U=85