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Table 1 Immunologic profile of the index patient

From: Leukocytoclastic vasculitis in patients with IL12B or IL12RB1 deficiency: case report and review of the literature

Parameters

Patient

Normal ranges

WBC ×  103 (cell/uL)

5.3

4.5–13.5

Hemoglobin (g/dL)

7.7

11.5–15.5

Monocytes (cell/uL)

0.5

0.2–0.8

Lymphocytes (cell/uL)

1.5

1.3–6.5

Neutrophils (cell/uL)

3.0

1.5–9.5

CD3+ T cells (% of lymphocytes)

63.9%

62.6–80.4 (%)

CD4+ T cells (% of T cells)

31.4%

32.6–51.5 (%)

CD8+ T cells (% of T cells)

20.8%

19.0–29.0 (%)

CD19+ (% of lymphocytes)

6.9%

11.9–21.0 (%)

CD16+ 56+ (% of lymphocytes)

12.3%

4.3–16.2 (%)

IgG (mg/dL)

2700

503–1719

IgA (mg/dL)

425

42–295

IgM (mg/dL)

360

41–255

IgE (IU/mL)

100

< 100

ESR (mm/first hour)

125

< 17

NBT (%)

99

> 80

C3 (IU/mL)

110

88–206

C4 (IU/mL)

38

13–75

CH50 (IU/mL)

80

42–95

T cell response to BCG

1.9

> 2.5

T cell response to PHA

3.1

≥3

T cell response to Candida

–

> 2.5

PPD

Negative

 

ANA

Negative

Anti-CCP

Negative

p-ANCA

Negative

c-ANCA

Negative

  1. Ig immunoglobulin, WBC white blood cell, ESR erythrocyte sedimentation rate, NBT Nitro blue tetrazolium, ANA antinuclear antibody, Anti-CCP anti-cyclic citrullinated peptide CH50; 50% hemolytic complement activity, PHA phytohemagglutinin, BCG Bacillus Calmette-Guérin, PPD purified protein derivative, p-ANCA Perinuclear anti-neutrophil cytoplasmic antibodies, c-ANCA Antineutrophil cytoplasmic antibodies