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Table 3 Performance measures for the ACR 1997, SLICC 2012 and ACR/EULAR 2019 criteria according to first visit, first year and latest periods

From: Evaluating the performance of ACR, SLICC and EULAR/ACR classification criteria in childhood onset systemic lupus erythematosus

Criteria

Sensitivity (95% CI)

Specificity (95% CI)

PPV (95% CI)

NPV (95% CI)

ROC (95% CI)

Accuracy (95% CI)

ACR 1997

 1st visit

49% (40–59%)

96% (87–99%)

97% (88–99%)

46% (36–56%)

0.73 (0.67–0.78)

64% (56–71%)

 1st year

57% (47–66%)

96% (87–99%)

97% (90–99%)

50% (40–60%)

0.76 (0.71–0.82)

69% (61–76%)

 Latest

66% (56–74%)

96% (87–99%)

97% (91–99%)

56% (45–66%)

0.81 (0.76–0.86)

75% (68–81%)

SLICC

 1st visit

76% (67–84%)

94% (84–99%)

97% (91–99%)

64% (52–75%)

0.85 (0.80–0.90)

82% (75–87%)

 1st year

84% (76–90%)

94% (84–99%)

97% (91–99%)

73% (60–83%)

0.89 (0.84–0.94)

87% (81–92%)

 Latest

86% (78–92%)

94% (84–99%)

97% (92–99%)

75% (63–85%)

0.90 (0.85–0.95)

88% (83–93%)

ACR/EULAR

 1st visit

81% (73–88%)

92% (81–98%)

96% (90–99%)

69% (57–80%)

0.87 (0.82–0.92)

85% (78–90%)

 1st year

88% (80–93%)

90% (79–97%)

95% (89–98%)

77% (64–87%)

0.89 (0.84–0.94)

88% (83–93%)

 Latest

89% (82–94%)

90% (79–97%)

95% (89–99%)

79% (67–89%)

0.90 (0.85–0.95)

90% (84–94%)

ACR/EULARa

 1st visit

76% (67–84%)

96% (87–99%)

98% (92–99%)

65% (53–75%)

0.86 (0.81–0.91)

83% (76–88%)

 1st year

83% (74–89%)

96% (87–99%)

98% (93–99%)

71% (59–81%)

0.89 (0.85–0.94)

87% (81–92%)

 Latest

84% (76–90%)

96% (87–99%)

98% (93–99%)

73% (61–83%)

0.90 (0.86–0.94)

88% (83–93%)

  1. ACR/EULARa, a score of ≥13 as compared to the traditional cut of score of ≥10
  2. The median disease duration was 5 (2.5–9) years with a range of 1–19 years
  3. ACR American College of Rheumatology 1997, SLICC Systemic Lupus Erythematosus International Collaborating Clinics, EULAR European League Against Rheumatism, CI Confidence interval, PPV Positive predictive value, NPV Negative predictive value, ROC Area under the received operating curve