Table 3 Serum concentration of immunoglobulins and complement components
From: IgA vasculitis nephritis clinical course and kidney biopsy – national study in children
Nephrotic proteinuria + hematuria Gr.A N = 55 | Non-nephrotic proteinuria + hematuria Gr B N = 38 | Isolated hematuria Gr C N = 13 | P | |
|---|---|---|---|---|
Serum IgA (mg/dl) | 213.23 +/− 100.3 | 252.52+/− 110.58 | 246.38 +/− 130.94 | NS |
Number of patients with elevated IgA (n%) | 16 (15%) | 17 (16%) | 7 (7%) | NS |
Serum C3 (mg/dl) | 114.56 +/− 31.56 | 121.22 +/− 26.56 | 113.42 +/− 16.22 | NS |
Number of patients with desreased C3 level (n%) | 10 (9%) | 1 (1%) | 0 (0%) | < 0.05* |
Serum C4 (mg/dl) | 23.79 +/− 9.15 | 26.43 +/−11.03 | 26.55 +/− 8.08 | NS |
Number of patients with desreased C4 level (n%) | 9 (8%) | 5 (5%) | 0 (0%) | < 0.05** |
Number of patients with desreased C3 and C4 levels (n%) | 5 (5%) | 0 (0%) | 0 (0%) | < 0.05*** |