Efficacy and safety associated with the infusion speed of intravenous immunoglobulin for the treatment of Kawasaki disease: a randomized controlled trial

Table 3 Laboratory data

		Day 0	Day 2	Day 7	p value
White blood cell count, 10⁹/L	12H	12.4 ± 3.4	8.6 ± 3.9	9.1 ± 4.0	0.585
White blood cell count, 10⁹/L	24H	12.4 ± 4.0	7.5 ± 3.7	7.9 ± 2.8	0.585
Neutrophils, %	12H	71.2 ± 13.3	46.1 ± 18.4	40.8 ± 12.6	0.732
Neutrophils, %	24H	67.2 ± 15.6	44.6 ± 19.2	40.2 ± 15.2	0.732
Platelet count, 10¹⁰/L	12H	31.1 ± 7.3	32.3 ± 10.8	54.9 ± 18.2	0.884
Platelet count, 10¹⁰/L	24H	36.2 ± 9.3	38.3 ± 11.5	58.6 ± 14.9	0.884
Albumin, g/L	12H	3.3 ± 0.4	2.7 ± 0.4	3.4 ± 0.6	0.471
Albumin, g/L	24H	3.5 ± 0.4	3.0 ± 0.4	3.6 ± 0.5	0.471
Creatinine, mg/dL	12H	0.27 ± 0.06	0.24 ± 0.04	0.25 ± 0.05	0.645
Creatinine, mg/dL	24H	0.27 ± 0.07	0.26 ± 0.07	0.26 ± 0.06	0.645
Aspartate aminotransferase, U/L	12H	100 ± 159	56 ± 92	39 ± 19	0.186
Aspartate aminotransferase, U/L	24H	38 ± 21	34 ± 13	37 ± 11	0.186
Sodium, mEq/L	12H	133 ± 3	137 ± 2	138 ± 2	< 0.01
Sodium, mEq/L	24H	137 ± 3	138 ± 3	138 ± 2	< 0.01
C-reactive protein, mg/dL	12H	7.3 ± 3.9	5.2 ± 3.5	0.7 ± 0.9	0.509
C-reactive protein, mg/dL	24H	6.4 ± 3.9	4.0 ± 5.4	0.8 ± 1.6	0.509
IgG, mg/dL	12H	624 ± 155	2414 ± 248	–	< 0.01
IgG, mg/dL	24H	754 ± 167	3037 ± 648	–	< 0.01

The value of serum IgG at day 7 was excluded because the value might change depending on whether the additional IVIG was given or not
Data are mean ± SD
IgG indicates immunoglobulin G
12H indicates 12 h. 24H indicates 24 h

ISSN: 1546-0096