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Fig. 3 | Pediatric Rheumatology

Fig. 3

From: A case of dermatomyositis in a patient with central core disease: unusual association with autoimmunity and genetic muscle disease

Fig. 3

Histological findings in a muscle biopsy specimen obtained from the vastus lateralis. A NADH-tetrazolium reductase stain shows irregularly outlined central cores in the type I myofibers (bar: 200 μm). B ATPase pH 4.3 shows pale central cores in the type I myofibers (bar: 200 μm). Electron microscopy (adenyl acetate and lead citrate stain) shows C a structured central core composed of randomly scattered short Z-bands and fine filaments (arrow) (bar: 5 μm), and D two tubuloreticular bodies (arrows) in the endothelial cells (bar: 500 nm)

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