|
Parameters
|
Measles
|
Mumps
|
Rubella
|
Diphtheria
|
Hepatitis B
|
|---|
|
HR (95%CI)
|
р
|
HR (95%CI)
|
р
|
HR (95%CI)
|
р
|
HR (95%CI)
|
р
|
HR (95%CI)
|
р
|
|---|
|
soJIA, yes
|
1.84 (0.84; 4.03)
|
0.128
|
1.43 (0.53; 3.95)
|
0.492
|
0.99 (0.05; 18.6)
|
0.995
|
2.04 (0.91;4.59)
|
0.08
|
2.52 (1.27; 5.0)
|
0.008
|
|
GCS, yes
|
1.54 (0.91; 2.61)
|
0.104
|
0.31 (0.45;1.84)
|
0.799
|
0.736 (0.11; 4.88)
|
0.736
|
1.89 (1.1; 3.24)
|
0.02
|
1.34 (0.77; 2.32)
|
0.295
|
|
МТХ, yes
|
0.86 (0.39; 1.88)
|
0.703
|
1.55 (0.49; 4.88)
|
0.453
|
1.53 (0.08; 28.64)
|
0.776
|
2.02 (0.71; 5.76)
|
0.187
|
0.6 (0.31; 1.15)
|
0.122
|
|
Biologics, yes
|
2.02 (1.22; 3.32)
|
0.006
|
1.76 (0.98; 3.15)
|
0.057
|
2.26 (0.5; 9.87)
|
0.293
|
1.67 (0.99; 2.8)
|
0.053
|
1.2 (0.75; 1.92)
|
0.453
|
|
> 1 biologics, consequent, yes
|
1.57 (1.13; 2.2)
|
0.007
|
1.4 (0.93; 2.09)
|
0.104
|
1.82 (0.71; 4.7)
|
0.213
|
1.4 (0.98; 2.0)
|
0.062
|
1.11 (0.78; 1.58)
|
0.572
|
|
Incomplete vaccination, yes
|
2.02 (1.02; 4.0)
|
0.042
|
6.25 (2.13; 17.9)
|
0.00008
|
na*
|
na*
|
2.39 (1.18; 4.85)
|
0.016
|
na*
|
na*
|
- Footnotes: CI confidence interval, GCS glucocorticosteroids, HR hazard ratio, MTX methotrexate, na not applicable, soJIA systemic onset of juvenile idiopathic arthritis. * Data was not calculated due to a small number of patients with a non-protective level of antibodies against rubella and no patients with incomplete vaccination against hepatitis B.
