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Table 3 Risk factors associated with non-protective levels of antibodies against measles, mumps, rubella, diphtheria, and hepatitis B vaccines (proportional hazard Cox regression models)

From: The vaccine coverage and vaccine immunity status and risk factors of non-protective levels of antibodies against vaccines in children with juvenile idiopathic arthritis: cross-sectional Russian tertiary Centre study

Parameters

Measles

Mumps

Rubella

Diphtheria

Hepatitis B

HR (95%CI)

Ñ€

HR (95%CI)

Ñ€

HR (95%CI)

Ñ€

HR (95%CI)

Ñ€

HR (95%CI)

Ñ€

soJIA, yes

1.84 (0.84; 4.03)

0.128

1.43 (0.53; 3.95)

0.492

0.99 (0.05; 18.6)

0.995

2.04 (0.91;4.59)

0.08

2.52 (1.27; 5.0)

0.008

GCS, yes

1.54 (0.91; 2.61)

0.104

0.31 (0.45;1.84)

0.799

0.736 (0.11; 4.88)

0.736

1.89 (1.1; 3.24)

0.02

1.34 (0.77; 2.32)

0.295

МТХ, yes

0.86 (0.39; 1.88)

0.703

1.55 (0.49; 4.88)

0.453

1.53 (0.08; 28.64)

0.776

2.02 (0.71; 5.76)

0.187

0.6 (0.31; 1.15)

0.122

Biologics, yes

2.02 (1.22; 3.32)

0.006

1.76 (0.98; 3.15)

0.057

2.26 (0.5; 9.87)

0.293

1.67 (0.99; 2.8)

0.053

1.2 (0.75; 1.92)

0.453

> 1 biologics, consequent, yes

1.57 (1.13; 2.2)

0.007

1.4 (0.93; 2.09)

0.104

1.82 (0.71; 4.7)

0.213

1.4 (0.98; 2.0)

0.062

1.11 (0.78; 1.58)

0.572

Incomplete vaccination, yes

2.02 (1.02; 4.0)

0.042

6.25 (2.13; 17.9)

0.00008

na*

na*

2.39 (1.18; 4.85)

0.016

na*

na*

  1. Footnotes: CI confidence interval, GCS glucocorticosteroids, HR hazard ratio, MTX methotrexate, na not applicable, soJIA systemic onset of juvenile idiopathic arthritis. * Data was not calculated due to a small number of patients with a non-protective level of antibodies against rubella and no patients with incomplete vaccination against hepatitis B.