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Table 2 Levels of antibodies against vaccines in JIA patients depend on vaccine coverage

From: The vaccine coverage and vaccine immunity status and risk factors of non-protective levels of antibodies against vaccines in children with juvenile idiopathic arthritis: cross-sectional Russian tertiary Centre study

Parameters

MMR vaccination for age

p*

Whole group (n = 170)

Incomplete (n = 50)

Complete (n = 120)

Anti-measels IgG, IU/ml

0.2 (0.04; 0.53)

0.2 (0.0; 0.5)

0.2 (0.09; 0.6)

0.181

Patients with anti-measles protective IgG level, n (%)

98 (57.7)

25 (50)

73 (60.8)

0.193

Anti-mumps IgG, IU/ml

2.7 (1.2; 5.3)

1.9 (0.0; 5.1)

2.9 (1.3; 5.3)

0.101

Patients with anti-mumps protective IgG level

136 (80,0)

35 (70.0)

101 (84.2)

0.035

Anti-rubella IgG, IU/ml

79.1 (43.0; 185.1)

69.9 (36.9; 119.6)

87.3 (45.3; 198.3)

0.173

Patients with anti-rubella protective IgG level, n (%)

168 (98.2)

49 (98.0)

119 (99.2)

0.520

Time since the last MMR vaccination, years

7.3 (5.0; 10.3)

5.5 (4.0; 7.5)

7.6 (4.9; 10.6)

0.156

 

Diphtheria vaccination

p*

Whole group (n = 170)

Incomplete (n = 85)

Complete (n = 85)

Anti-diphtheria IgG, IU/ml

0.12 (0.04; 0.31)

0.07 (0.03; 0.22)

0.2 (0.06; 0.4)

0.001

Patients with anti-diphtheria protective IgG level, n (%)

88 (51,8)

34 (40.0)

54 (63.5)

0.002

Time since last diphtheria vaccination, years

6.0 (4.1; 9.6)

5.4 (4.1; 9.0)

6.1 (4.8; 9.3)

0.468

  1. *no data due to complete hepatitis B vaccination