Factors affecting the duration of coronary artery lesions in patients with the Kawasaki disease: a retrospective cohort study

Table 4 Factors associated with CAL duration

	Univariate		Multivariate
	HR (95% CI)	P value	HR(95% CI)	P value
Sex
Male	Reference	1.00	Reference	1.00
Female	1.334 (1.055–1.686)	0.016^*	1.215 (0.958–1.540)	0.108
Rash
Yes	Reference	1.00	Reference	1.00
No	1.295 (1.019–1.645)	0.035^*	0.976 (0.761–1.251)	0.846
IVIG treatment
Not delayed	Reference	1.00	Reference	1.00
Delayed	0.672 (0.515–0.875)	0.022^*	0.722 (0.550–0.950)	0.020^*
CAL type
Single	Reference	1.00	Reference	1.00
Multiple	0.382 (0.294–0.496)	<0.001^*	0.516 (0.392–0.677)	<0.001^*
Degree of CAL
Only dilation	Reference	1.00	Reference	1.00
Aneurysm	0.246 (0.158–0.382)	<0.001^*	0.319 (0.202–0.505)	<0.001^*
Laboratory data
White blood cell count before IVIG	0.979 (0.962–0.997)	0.019	1.004 (0.981–1.020)	0.971
Platelet count after IVIG	0.999 (0.998–0.999)	0.003	0.9992 (0.9986–0.9998)	0.007^*

Abbreviations: CAL coronary artery lesion; IVIG intravenous immunoglobulin; HR hazard ratio
Delayed IVIG was defined as the administration of IVIG > 10 days after disease onset
Single CAL was defined as CAL in one of the following arteries: LMCA LAD, LCX, RCA, or PDCA. Multiple CAL was defined as CAL in more than one of these arteries
Dilation was defined as an absolute diameter of the coronary artery of < 4 mm
Aneurysm was defined as an absolute diameter of the coronary artery of ≥4 mm

ISSN: 1546-0096