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Table 1 Characteristics of patients at time of histoplasmosis diagnosis. Information was collected on patient demographics and IM prior to histoplasmosis diagnosis

From: Reintroduction of immunosuppressive medications in pediatric rheumatology patients with histoplasmosis: a case series

Patient

Age (yr) at Histoplasmosis Diagnosis, Sex

Rheumatic Disease

Anti-TNFa (duration of Therapy in Months Prior to Histoplasmosis Diagnosis)

Other Pre-histoplasmosis IM (month duration)

1

11, F

JIA, Psoriatic

Adalimumab (0.5)

MTX (5)

2

17, F

JIA, Poly

Etanercept (1.3)

MTX (7), burst steroids (1)

3

18, F

JIA, Psoriatic

Infliximab (14.1)

MTX (23)

4

15, F

cSLE

-

MTX (3), HCQ (5), burst steroids (12.8)

5

16, F

JIA, Enthesitis

-

None

6

9, M

JIA, Enthesitis

Adalimumab (1.3)

MTX (15)

7

17, F

JIA, Oligo

-

MTX (18)

8

16, M

MCTD

-

MTX (31), HCQ (32), maintenance steroids (30)

9

5, F

JIA, Poly

-

None

Summary, % or Median (range):

16 [5,6,7,8,9,10,11,12,13,14,15,16,17,18],

78 % F

7 JIA, 1 cSLE, 1 MCTD

44 % TNFai, 1.3 (0.5–14.1)

78 % DMARD, 18 (4.6–32)

33 % Steroids, 13 (0.6–30)

  1. Key: Pt = patient identifier; yr = years; IM = immunosuppressive medication; JIA = juvenile idiopathic arthritis, MTX = methotrexate, Poly = polyarticular; cSLE = childhood-onset systemic lupus erythematosus; HCQ = hydroxychloroquine; Oligo = oligoarticular; MCTD = mixed connective tissue disease