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Fig. 2 | Pediatric Rheumatology

Fig. 2

From: Necrotizing Funisitis as an Intrauterine manifestation of Cryopyrin-Associated Periodic Syndrome: a case report and review of the literature

Fig. 2

Microscopic findings of the placenta and umbilical cord. A. Necrotizing funisitis: the umbilical cord showed ring-shaped infiltration of inflammatory cells around the artery (arrow and inset), but not in the vein (arrow head). (Hematoxylin an eosin (HE) staining). B. Focal neutrophilic and lymphocytic villitis: destructive inflammation of chorionic villus (arrow), followed by mild collapse of villous vessels (HE staining). C. The chorioamnion without neutrophilic infiltration. D. Immunohistochemical staining of myeloperoxidase: the inflammation around the umbilical artery and perivascular Wharton’s jelly caused mainly by macrophages and neutrophils

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Pediatric Rheumatology

ISSN: 1546-0096