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Table 2 Levels of short chain fatty acids (SCFAs) in faecal samples before, compared with at four weeks of treatment with specific carbohydrate diet (SCD) in fifteen patients with juvenile idiopathic arthritis

From: A pilot study of possible anti-inflammatory effects of the specific carbohydrate diet in children with juvenile idiopathic arthritis

SCFA mg/ga

At inclusion Md (IQR)b

At 4 weeks of SCD

Median difference

Confidence interval*

p-value **

Butyrate

0.7 (0.4–1.3)

1.2 (0.9–2.0)

0.5

0.08–1.0

0.02

Propionate

0.9 (0.5–1.0)

0.9 (0.6–1.3)

0.2

(− 0.01)–(0.4)

0.06

Acetate

3.0 (2.2–3.7)

3.7 (2.1–5.3)

0.4

(−0.5)–(1.1)

0.3

Valerate

0.1 (0.04–0.2)

0.1 (0.06–0.2)

0.02

(−0.05)–(0.1)

0.5

Total

5.4 (3.6–6.8)

6.6 (4.2–8.5)

1.1

(−0.2)–(2.4)

0.07

  1. amg = milligram; g = gram
  2. bMd = median; IQR = interquartile range
  3. *Hodges-Lehmann related sample analysis
  4. **Wilcoxon matched-pair signed rank analysis