Skip to main content

Table 1 Clinical information of children with Kawasaki disease regarding IVIG responsiveness at admission day

From: The “Intermediate” CD14 + CD16 + monocyte subpopulation plays a role in IVIG responsiveness of children with Kawasaki disease

 

Total (n = 62)

IVIG-responsive (n = 50)

IVIG-resistant (n = 12)

P-Value

Age

2.6 ± 2.2

2.6 ± 2.2

2.5 ± 2.3

0.82

Male (n, %)

35 (56.4 %)

28(56 %)

7(58.3 %)

0.88

Body weight (kg)

14.9 ± 6.3

14.7 ± 5.5

15.6 ± 9.2

0.82

Symptoms (n, %)

 Rash

56 (90.3 %)

44(88.0 %)

12(100.0 %)

0.21

 Red lip, Red tongue

55 (88.7 %)

43(86.0 %)

12(100.0 %)

0.17

 Desquamation

35 (58.3 %)

26(54.2 %)

9(75.0 %)

0.19

 Conjunctivitis

56 (90.3 %)

44(88.0 %)

12(100.0 %)

0.21

 Cervical lymphadenopathy

34 (54.8 %)

28(56.0 %)

6(50.0 %)

0.71

 Edema of extremity

41 (66.1 %)

31(62.0 %)

10(83.3 %)

0.16

 Coronary artery dilatation

6 (9.7 %)

3 (25 %)

3 (6 %)

0.04

Laboratory findings

 WBC (k/mm3)

15.2 ± 5.8

14.8 ± 6.0

17.5 ± 4.5

0.28

 Neutrophil (k/mm3)

10.7 ± 7.5

9.7 ± 5.5

15.5 ± 12.3

0.01

 Lymphocyte (k/mm3)

3.6 ± 2.3

3.6 ± 2.3

3.3 ± 2.2

0.63

 Monocyte (k/mm3)

0.9 ± 0.5

0.9 ± 0.5

0.8 ± 0.6

0.64

 NLR

4.9 ± 4.8

4.2 ± 3.7

7.9 ± 7.4

0.01

 Hemoglobin

11.3 ± 1.04

11.3 ± 0.9

11.2 ± 1.5

0.81

 Total bilirubin

0.7 ± 0.8

0.5 ± 0.4

1.3 ± 1.4

0.26

 Platelet

352.5 ± 113.5

348.3 ± 106.6

370.0 ± 142.8

0.78

 Albumin

3.7 ± 0.5

3.7 ± 0.5

3.3 ± 0.4

< 0.01

 ESR

71.9 ± 29.7

74.7 ± 30.1

63.7 ± 28.7

0.34

 CRP

8.5 ± 5.7

8.0 ± 5.5

10.3 ± 6.3

0.21

Treatment

 1st IVIG

60 (96.8 %)

48(96.0 %)

12(100 %)

< 0.01

 2nd IVIG

12 (19.3 %)

0(0.0 %)

12(100 %)

< 0.01

 Steroid

5 (8.1 %)

0(0.0 %)

5(41.7 %)

< 0.01

 Infliximab

1 (1.6 %)

0(0.0 %)

1(8.3 %)

0.04

 Aspirin

61 (98.4 %)

49(98.0 %)

12(100.0 %)

0.50

 Clopidogrel

2 (3.2 %)

2(4.0 %)

0(0.0 %)

0.50

  1. CRP C-reactive protein, ESR erythrocyte sedimentation rate, IVIG intravenous immunoglobulin, NLR neutrophil to lymphocyte ratio, WBC white blood cells