Total (n = 62) | IVIG-responsive (n = 50) | IVIG-resistant (n = 12) | P-Value | |
---|---|---|---|---|
Age | 2.6 ± 2.2 | 2.6 ± 2.2 | 2.5 ± 2.3 | 0.82 |
Male (n, %) | 35 (56.4 %) | 28(56 %) | 7(58.3 %) | 0.88 |
Body weight (kg) | 14.9 ± 6.3 | 14.7 ± 5.5 | 15.6 ± 9.2 | 0.82 |
Symptoms (n, %) | ||||
Rash | 56 (90.3 %) | 44(88.0 %) | 12(100.0 %) | 0.21 |
Red lip, Red tongue | 55 (88.7 %) | 43(86.0 %) | 12(100.0 %) | 0.17 |
Desquamation | 35 (58.3 %) | 26(54.2 %) | 9(75.0 %) | 0.19 |
Conjunctivitis | 56 (90.3 %) | 44(88.0 %) | 12(100.0 %) | 0.21 |
Cervical lymphadenopathy | 34 (54.8 %) | 28(56.0 %) | 6(50.0 %) | 0.71 |
Edema of extremity | 41 (66.1 %) | 31(62.0 %) | 10(83.3 %) | 0.16 |
Coronary artery dilatation | 6 (9.7 %) | 3 (25 %) | 3 (6 %) | 0.04 |
Laboratory findings | ||||
WBC (k/mm3) | 15.2 ± 5.8 | 14.8 ± 6.0 | 17.5 ± 4.5 | 0.28 |
Neutrophil (k/mm3) | 10.7 ± 7.5 | 9.7 ± 5.5 | 15.5 ± 12.3 | 0.01 |
Lymphocyte (k/mm3) | 3.6 ± 2.3 | 3.6 ± 2.3 | 3.3 ± 2.2 | 0.63 |
Monocyte (k/mm3) | 0.9 ± 0.5 | 0.9 ± 0.5 | 0.8 ± 0.6 | 0.64 |
NLR | 4.9 ± 4.8 | 4.2 ± 3.7 | 7.9 ± 7.4 | 0.01 |
Hemoglobin | 11.3 ± 1.04 | 11.3 ± 0.9 | 11.2 ± 1.5 | 0.81 |
Total bilirubin | 0.7 ± 0.8 | 0.5 ± 0.4 | 1.3 ± 1.4 | 0.26 |
Platelet | 352.5 ± 113.5 | 348.3 ± 106.6 | 370.0 ± 142.8 | 0.78 |
Albumin | 3.7 ± 0.5 | 3.7 ± 0.5 | 3.3 ± 0.4 | < 0.01 |
ESR | 71.9 ± 29.7 | 74.7 ± 30.1 | 63.7 ± 28.7 | 0.34 |
CRP | 8.5 ± 5.7 | 8.0 ± 5.5 | 10.3 ± 6.3 | 0.21 |
Treatment | ||||
1st IVIG | 60 (96.8 %) | 48(96.0 %) | 12(100 %) | < 0.01 |
2nd IVIG | 12 (19.3 %) | 0(0.0 %) | 12(100 %) | < 0.01 |
Steroid | 5 (8.1 %) | 0(0.0 %) | 5(41.7 %) | < 0.01 |
Infliximab | 1 (1.6 %) | 0(0.0 %) | 1(8.3 %) | 0.04 |
Aspirin | 61 (98.4 %) | 49(98.0 %) | 12(100.0 %) | 0.50 |
Clopidogrel | 2 (3.2 %) | 2(4.0 %) | 0(0.0 %) | 0.50 |