Table 2 Response to treatment and coronary artery complications in children with Kawasaki disease
Outcomes | Total n (%) | Low CRP < 3 mg/dL (n = 2107), n (%) | High CRP ≥ 3 mg/dL (n = 7024), n (%) | p-value | ||
|---|---|---|---|---|---|---|
Spontaneous remission | 341 (3.7) | 174 (8.3) | 167 (2.4) | < 0.001 | ||
1st IVIG | 8778 (96.1) | 1929 (91.6) | 6849 (97.5) | < 0.001 | ||
Unresponsive to 1st IVIG | 1602/8778 (18.3) | 225 (11.7) | 1377 (20.1) | < 0.001 | ||
2nd IVIG | 1435/1602 (89.6) | 198 (88.0) | 1237 (89.8) | 0.453 | ||
Unresponsive to 2nd IVIG | 342/1435 (23.8) | 40 (20.2) | 302 (24.4) | 0.209 | ||
Acute CAL | ||||||
z-score | 1271/9000 (14.1) | 2082 | 380 (18.3) | 6918 | 891 (12.9) | < 0.001 |
Japanese criteria | 946/9014 (10.5) | 2084 | 260 (12.5) | 6930 | 686 (9.9) | 0.001 |
Acute giant CAA | ||||||
z-score | 56/9014 (0.6) | 2084 | 13 (0.6) | 6930 | 43 (0.6) | 1.0 |
Japanese criteria | 13/9110 (0.1) | 2101 | 3 (0.1) | 7009 | 10 (0.1) | 1.0 |
Convalescent CAL | ||||||
z-score | 501/8196 (6.1) | 1873 | 160 (8.5) | 6323 | 341 (5.4) | < 0.001 |
Japanese criteria | 419/8203 (5.1) | 1875 | 127 (6.8) | 6328 | 292 (4.6) | < 0.001 |
Convalescent giant CAA | ||||||
z-score | 28/8204 (0.3) | 1875 | 1 (0.1) | 6329 | 27 (0.4) | 0.011 |
Japanese criteria | 8/8661 (0.1) | 1971 | 0 | 6690 | 8 (0.1) | 0.212 |