Table 1 Clinical characteristics between patients with low and high C-reactive protein levels among patient with KD
Characteristics | Total | Low CRP < 3 mg/dL | High CRP ≥ 3 mg/dL | p-value | ||
|---|---|---|---|---|---|---|
n | Value | n | Value | |||
N (%) | 9131 | 2107 | 23.1 | 7024 | 76.9 | |
Age, months (mean ± SD) | 9131 | 2107 | 31.7 ± 24.8 | 7024 | 34.4 ± 24.9 | < 0.001 |
Male, n (%) | 9053 | 2081 | 1261 (60.6) | 6972 | 4042 (58.0) | 0.033 |
Weight, kg (mean ± SD) | 9131 | 2107 | 13.8 ± 6.0 | 7024 | 14.2 ± 5.9 | 0.003 |
Height, cm (mean ± SD) | 9131 | 2107 | 90.2 ± 17.4 | 7024 | 92.2 ± 17.3 | < 0.001 |
Fever, total days (mean ± SD) | 8810 | 2027 | 6.3 ± 2.5 | 6783 | 6.6 ± 2.2 | < 0.001 |
Fever, pretreatment, days (mean ± SD) | 9025 | 2072 | 5.2 ± 2.1 | 6998 | 5.1 ± 1.7 | 0.206 |
Symptoms, n (%) | ||||||
Conjunctival injection | 9010 | 2054 | 1664 (81.0) | 6956 | 6220 (89.4) | < 0.001 |
Oral changes | 9001 | 2050 | 1604 (78.2) | 6951 | 5865 (84.4) | < 0.001 |
Extremity changes | 8918 | 2028 | 1247 (61.5) | 6890 | 4651 (67.5) | < 0.001 |
Rash | 8984 | 2053 | 1484 (72.3) | 6931 | 5349 (77.2) | < 0.001 |
BCG site redness | 8354 | 1914 | 769 (40.2) | 6440 | 2520 (39.1) | 0.424 |
Cervical lymphadenopathy | 8960 | 2047 | 1015 (49.6) | 6913 | 4179 (60.5) | < 0.001 |
Incomplete presentation, n (%) | 8914 | 2006 | 844 (42.1) | 6908 | 2187 (31.7) | < 0.001 |
Family history, n (%) | 6543 | 1414 | 24 (1.7) | 5129 | 68 (1.3) | 0.312 |
Recurrence, n (%) | 8781 | 2017 | 99 (4.9) | 6763 | 337 (5.0) | 0.953 |
Laboratory results | ||||||
WBC, /mm3 (mean ± SD) | 9126 | 2106 | 11.988 ± 4.881 | 7020 | 14.818 ± 5.163 | < 0.001 |
Neutrophil, % (mean ± SD) | 9037 | 2066 | 52.2 ± 16.9 | 6971 | 66.5 ± 14.6 | < 0.001 |
Hemoglobin, g/dL (mean ± SD) | 9096 | 2100 | 11.6 ± 0.97 | 6996 | 11.3 ± 1.02 | < 0.001 |
Platelets, × 103 (mean ± SD) | 9105 | 2103 | 357.4 ± 126.8 | 7002 | 356.5 ± 109.8 | 0.765 |
Platelets, ×10 [3], highest (mean ± SD) | 8651 | 2002 | 422.6 ± 147.0 | 6649 | 483.6 ± 165.4 | < 0.001 |
Albumin, g/dL (mean ± SD) | 9093 | 2093 | 4.0 ± 0.3 | 7000 | 3.8 ± 0.4 | < 0.001 |
AST, IU/L (mean ± SD) | 9105 | 2100 | 64.6 ± 125.9 | 7005 | 94.0 ± 173.5 | < 0.001 |
ALT, IU/L (mean ± SD) | 9095 | 2096 | 59.8 ± 131.5 | 6999 | 100.1 ± 149.3 | < 0.001 |
Total bilirubin, mg/dL (mean ± SD) | 8978 | 2070 | 0.4 ± 0.47 | 6908 | 0.68 ± 0.83 | < 0.001 |
Na, mEq/L (mean ± SD) | 8983 | 2059 | 137.0 ± 2.4 | 6924 | 136.2 ± 2.7 | < 0.001 |
CRP, mg/dL (mean ± SD) | 9131 | 2107 | 1.59 ± 0.86 | 7024 | 9.20 ± 5.49 | < 0.001 |
ESR, mm/hr. (mean ± SD) | 8356 | 1919 | 41.5 ± 24.9 | 6437 | 60.7 ± 26.7 | < 0.001 |
BNP, pg/mL (mean ± SD) | 2079 | 519 | 55.3 ± 94.0 | 1559 | 199.4 ± 597.3 | < 0.001 |
ProBNP, pg/mL (mean ± SD) | 5533 | 1266 | 551.5 ± 1081.5 | 4267 | 1624.2 ± 3400.8 | < 0.001 |
Pyuria, n (%) | 9008 | 2076 | 409 (19.7) | 6932 | 2652 (38.3) | < 0.001 |