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Table 3 Demographics, disease characteristics, and patient-reported measures of patients with normal vs. abnormal salivary gland ultrasound studies

From: Findings and feasibility of major salivary gland ultrasound in childhood-onset systemic lupus erythematosus: a pilot study

 

Normal US N = 20 (%)a

Abnormal US N = 11 (%)a

p-value

Demographics

 Age, years, Mean (SD)

18.0 (2.5)

19.6 (2.6)

0.11

 Female

18 (90)

9 (82)

1.00

 Caucasian

13 (65)

4 (36)

0.15

 Black/African American

6 (30)

7 (64)

0.13

Disease characteristics

 Disease Duration, years, Mean (SD)

4.5 (3.5)

5.9 (3.6)

0.31

 SLEDAIb, Median (IQR)

2.0 (0.0–4.0)

4.0 (1.0–5.0)

0.74

 Anti-dsDNAc

15 (75)

6 (55)

0.24

 Anti-Smithc

10 (50)

6 (55)

1.00

 Anti-RNPc

13 (65)

9 (82)

0.43

 Anti-Roc

6 (30)

9 (82)

0.01

 Anti-Lac

1 (5)

4 (36)

0.04

 IgGd mg/dL, Mean (SD)

1323.4 (559.6)

2017.3 (825.7)

0.01

Patient-reported measures

 Dryness Scoree, Median (IQR)

0.5 (0.0–3.0)

3.0 (1.5–5.0)

0.09

 Fatigue Scoree, Median (IQR)

2.5 (0.8–4.0)

2.0 (1.0–5.5)

0.80

 Pain Scoree, Median (IQR)

1.0 (0.0–3.0)

1.0 (0.0–4.0)

0.86

 Needs water to swallow

4 (20)

3 (27)

0.68

 Episodic cheek swelling

3 (15)

1 (9)

1.00

  1. a Number of patients with percentage unless noted; b SLEDAI: Systemic Lupus Erythematosus Disease Activity Index, most recent value; cAny history of antibody positivity; d IgG level at disease diagnosis; eDryness, Fatigue, and Pain scores on a scale of 0–10 with 10 being the worst score