Normal US N = 20 (%)a | Abnormal US N = 11 (%)a | p-value | |
---|---|---|---|
Demographics | |||
Age, years, Mean (SD) | 18.0 (2.5) | 19.6 (2.6) | 0.11 |
Female | 18 (90) | 9 (82) | 1.00 |
Caucasian | 13 (65) | 4 (36) | 0.15 |
Black/African American | 6 (30) | 7 (64) | 0.13 |
Disease characteristics | |||
Disease Duration, years, Mean (SD) | 4.5 (3.5) | 5.9 (3.6) | 0.31 |
SLEDAIb, Median (IQR) | 2.0 (0.0–4.0) | 4.0 (1.0–5.0) | 0.74 |
Anti-dsDNAc | 15 (75) | 6 (55) | 0.24 |
Anti-Smithc | 10 (50) | 6 (55) | 1.00 |
Anti-RNPc | 13 (65) | 9 (82) | 0.43 |
Anti-Roc | 6 (30) | 9 (82) | 0.01 |
Anti-Lac | 1 (5) | 4 (36) | 0.04 |
IgGd mg/dL, Mean (SD) | 1323.4 (559.6) | 2017.3 (825.7) | 0.01 |
Patient-reported measures | |||
Dryness Scoree, Median (IQR) | 0.5 (0.0–3.0) | 3.0 (1.5–5.0) | 0.09 |
Fatigue Scoree, Median (IQR) | 2.5 (0.8–4.0) | 2.0 (1.0–5.5) | 0.80 |
Pain Scoree, Median (IQR) | 1.0 (0.0–3.0) | 1.0 (0.0–4.0) | 0.86 |
Needs water to swallow | 4 (20) | 3 (27) | 0.68 |
Episodic cheek swelling | 3 (15) | 1 (9) | 1.00 |