Bone mineral density and explanatory factors in children and adults with juvenile dermatomyositis at long term follow-up; a cross sectional study

Table 5 Associations between BDM and BMD Z-score and: prednisolone and bone remodeling factors in JDM patients and controls, younger and older than 20 years

	Patients	Controls	Patients	Controls	Patients	Controls
	Total	Total	Age < 20y	Age < 20y	Age ≥ 20y	Age ≥ 20y
BMD Z-score, Whole body
Prednisolone use at FU	−0.26	NA	−0.26	NA	−0.20	NA
Prednisolone use (month)	0.18	NA	−0.36	NA	0.43*	NA
PTH	− 0.30*	0.01	− 0.29	0.15	− 0.33	− 0.12
IP-10	− 0.34*	0.16	− 0.38	0.14	− 0.38*	0.25
hsCRP	−0.15	0.234	−0.21	0.54**	−0.22	0.07
BMD Z-score, Lumbar spine
Prednisolone use at FU	−0.41*	NA	−0.45*	NA	−0.34	NA
Prednisolone use (month)	0.01	NA	−0.40*	NA	0.18	NA
Cumulative prednisolone	0.00	NA	−0.48*	NA	0.15	NA
IP-10	−0.21	0.20	−0.42*	0.10	−0.19	0.19
hsCRP	−0.24	0.19	−0.19	0.39*	−0.40*	0.03

FU follow up, 25-OH-VitD 25-hydroxyvitamin D, IP-10 interferon gamma-induced protein 10, hsCRP high sensitive C-reactive protein, NA not applicable All values are Spearmans correlation or point bi-serial correlations when appropriate, * p < 0.05, **p < 0

ISSN: 1546-0096