Fecal microbiota in children with juvenile idiopathic arthritis treated with methotrexate or etanercept

Table 3 Differences in relative abundances of taxa between treatment-naïve children and children treated with MTX or ETN

Taxa influenced by medical treatment^a	Treatment-naïve (n = 45)	MTX (n = 29)	ETN (n = 15)	Crude p value*	Adjusted p value**
MTX:
Subdoligranulum (G)	0.028 (0.023)	0.065 (0.067)		0.005	0.27
ETN:
Lachnospiraceae_NK4A136_group (G)	0.016 (0.015)		0.031 (0.033)	0.04	1

^aSelected list of taxa with crude p value < 0.05. Data are mean (SE), unless otherwise indicated
*P values calculated using logistic regression with age at sampling as a covariate
**False discovery rate control using the Benjamini-Hochberg procedure
JIA Juvenile idiopathic arthritis, MTX Methotrexate, ETN Etanercept, RF Rheumatoid factor, F Family, G Genus, SE Standard error of the mean

ISSN: 1546-0096