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Table 2 Characteristics of 22 children with JIA, sampled both when treatment-naïve and during treatment

From: Fecal microbiota in children with juvenile idiopathic arthritis treated with methotrexate or etanercept

  Treatment-naïve (n = 15) MTX (n = 15) Treatment-naïve (n = 7) ETN (n = 7)
Female sex (%) 11 (73)   2 (29)  
Age at sampling, years 9.1 (4.1–11.0) 9.2 (4.6–11.1) 13.0 (8.0–14.9) 13.4 (8.5–15.8)
JIA onset to sampling, years 0.4 (0.1–1.7) 1.2 (0.8–2.2) 0.34 (0.3–1.3) 2.1 (1.0–2.7)
Start of medication to sampling, years   0.5 (0.3–0.7)   0.3 (0.2–0.3)
JIA category at onset, no (% girls)
 Oligoarticular   7 (86)   1 (100)
 Polyarticular RF neg   6 (67)   2 (0)
 Polyarticular RF pos   0   1 (100)
 Enthesitis-related   1 (0)   2 (0)
 Undifferentiated   1 (100)   1 (0)
  1. Data are median (1st–3rd quartile), unless otherwise indicated. Fifteen children were on single treatment with MTX, and 7 children were on ETN, as single treatment or in combination with MTX, at second sampling
  2. JIA Juvenile idiopathic arthritis, MTX Methotrexate, ETN Etanercept, RF Rheumatoid factor