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Table 2 Body mass index, disease activity and laboratory and lipid profile findings in children and adolescents with juvenile idiopathic arthritis according to HDL-c level

From: Biomarkers of lipid metabolism in patients with juvenile idiopathic arthritis: relationship with disease subtype and inflammatory activity

Variables

HDL-c

Adequate

n = 42

Borderline-low

n = 20

P

Pubescent, N (%)

33 (78.6)

9 (45)

0.559

BMI

17.9 (17–21.2)

18.6 (16.1–20.3)

0.952

Z-Score BMI/age > 1

7 (16.7)

6 (30)

0.228

CHAQ

0.27 (0.1–0.6)

0.55 (0.3–1.03)

0.292

 > 0, N (%)

10 (23.8)

7 (35)

0.356

Disease activity

 Active, N (%)

16 (38.1)

5 (25)

0.308

us-CRP

1.2 (0.5–4.9)

2.8 (0.9–15)

0.312

 ≥ 3

14 (33.3)

10 (50.0)

0.208

ESR

6.5 (5.0–30.0)

19.5 (6.0–32.0)

0.191

 ≥ 20

15 (35.7)

10 (50.0)

0.407

HDL-c

50.0 (45.0–59.0)

46.0 (42.0–49.0)

0.271

Borderline/Low N (%)

14 (28.6)

6 (46.2)

0.351

LDL-c

86.4 (72.2–103.0)

84.4 (71.2–99.4)

0.646

 Borderline/High

8 (19.0)

4 (20.0)

1.000

Triglycerides

66.5 (51.0–85.0)

62.0 (51.5–88.5)

0.821

 Borderline/High

12 (28.6)

5 (25.0)

1.000

Apo A-1

118.0 (108.0–137.0)

100.0 (92.0–106.5)

< 0.001

 Borderline/Low

23 (54.8)

19 (95.0)

0.001

Apo B

72.5 (58.0–84.0)

68.0 (58.5–83.5)

0.821

 Borderline/Low

5 (11.9)

4 (20.0)

0.453

NHDL-c

99.0 (87.0–124.0)

96.5 (82.5–119.5)

0.474

 Borderline/Low

12 (28.6)

5 (25.0)

1.000

  1. Tests: Fisher’s exact or Chi-square test, or Pearson or Mann-Whitney, p < 0.05; median (IQ: 25–75)
  2. BMI Body mass index, CHAQ Childhood Health Assessment Questionnaire, us-CRP Ultra-sensitive C reactive protein, ESR Erythrocyte sedimentation rate, LDL-c Low-density lipoprotein cholesterol, HDL-c High-density lipoprotein cholesterol, NHDL Non-high-density lipoprotein cholesterol, Apo A-I Apolipoprotein A-1, Apo B Apolipoprotein B