TY - JOUR AU - O’Leary, Daire AU - Wilson, Anthony G. AU - MacDermott, Emma-Jane AU - Lowry, Clodagh AU - Killeen, Orla G. PY - 2021 DA - 2021/03/25 TI - Variability in phenotype and response to treatment in chronic nonbacterial osteomyelitis; the Irish experience of a national cohort JO - Pediatric Rheumatology SP - 45 VL - 19 IS - 1 AB - Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory disease affecting bone with considerable phenotypic heterogeneity and variable association with other autoinflammatory conditions. Disease pathogenesis is incompletely understood, and treatment protocols vary between physicians with no clinical treatment guidelines available prior to 2017. Although CNO was previously considered benign, it is now clear that long-term sequelae do occur. SN - 1546-0096 UR - https://doi.org/10.1186/s12969-021-00530-4 DO - 10.1186/s12969-021-00530-4 ID - O’Leary2021 ER -