Monitoring patients with juvenile idiopathic arthritis using health-related quality of life

Table 3 Discriminatory power of EQ-5D-Y-5L thresholds to identify JIA patients with moderate to high disease activity

EQ-5D-Y-5L Thresholds	Accuracy (%)	95% CI	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
EQ-5D Sum Score > 6	87^*	76–94	85	89	88	86
EQ-VAS < 82	87^*	76–94	88	86	85	88
Mobility > 1	84^*	75–93	70	97	96	77
Self-Care > 1	72^*	60–88	42	100	100	65
Daily Activities > 1	79^*	68–88	82	77	77	82
Pain/Discomfort > 1	82^*	71–91	85	80	80	85
Anxiety/Depression > 1	78^*	66–87	61	94	91	72

^*P-value < 0.001; EQ-5D-Y-5L: EuroQol five-dimensional ‘youth’ questionnaire with five levels; EQ-5D sum score: unweighted sum of EQ-5D-Y-5L individual level scores (range 5–25); EQ-VAS: EuroQol visual analogue scale (range 0–100); NPV: negative predictive value; PPV: positive predictive value

ISSN: 1546-0096