Table 2 Results and outcome depending on the type of transplantation^a

HLA donor

Autologous stem cell transplantation (with T cell depletion)

Autologous stem cell transplantation (with T cell depletion)

MUD^b 9/16

MSD: 4/16

mMUD: 3/16

Age at HSCT (median)

9.1 years (range 4.2 to 18.2 years)

10.8 years (range 6 to 18 years)

21.5 months (range, 5 months to 12 years)

Follow up (median)

70 months (range 13–135 months)

80 months (range 60–96 months)

29 months (range, 2.8–8 years)

Deaths

2^d

1^e

2^f

Complete clinical remission

8/20

4/6

11/14

Partial responders

7/20

0/6

1/14

Relapse of the disease

5/20

2/6

1/14

Infections:

19/22

4/7

10/16

Viral^c (CMV, HSV, EBV, VZV, BK virus)

25

6

10

Bacterial

8

NC

3

Fungal

2

NC

1

Allo/auto-immune complications

–

1/6

4/14

GVHD (grade II-IV)

–

–

3/16