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Table 1 Immune reconstitution after transplantation

From: Sustained remission after haploidentical bone marrow transplantation in a child with refractory systemic juvenile idiopathic arthritis

Time after HSCT M + 3 M + 4 M + 5 M + 6 M + 9 M + 12 M + 18 M + 24 M + 36 Normal values in healthy children
Age (years) 3.8 46 47 48 51 54 60 66 78 2 to 6
CD3+ (cells/ μl) 186 346 197 324 394 447 1249 3451 4635 1400–3700
CD4+ (cells/ μl)
 - CD31+ CD45RA+ naive (%)
 -CD45RO+ memory (%)
158 278 131 211 254 305
24
68
866 2090
62
32
2754 700–2200
43–55
58–70
CD8+ (cells/ μl) 20 56 36 68 79 81 262 1118 1411 490–1300
 -CD45RA+CCR7+ naive (%)       55   41   52–68
 -CD45RACCR7+ central memory (%)       11   1,5   3–4
 -CD45RACCR7 effector memory (%)       28   4,5   11–20
 -CD45RA+CCR7 TEMRA (%)       6,5   13   16–28
CD19+ (cells/ μl) 154 208 55 102 307 417 624 1312 1948 390–1400
CD16+ 56+ (cells/ μl) 57 125 102 125 149 132 121 49 134 130–720
T cell proliferations (cpm/min/10^3)           
 -PHA, J3         72   >  50
  1. PHA phytohemagglutinin
  2. The patient achieved a CD4+ count > 400/μl at M4. Naïve T cells appeared at M12. The percentage was 24% for CD4 +CD31+CD45RA+ and 54% for CD8 +CD45RA+CCR7+