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Table 4 Rates and reasons for methotrexate discontinuation (several reasons could be given in parallel)

From: Outcome of children with oligoarticular juvenile idiopathic arthritis compared to polyarthritis on methotrexate- data of the German BIKER registry

  persistent oligoJIA extended oligoJIA RF negative PA
Discontinuations total [n, %] 198(100) 317 (100) 564 (100)
Inefficacy [n, %] 13 (6.8) 19 (6.2) 27 (5.0)
Intolerance [n, %] 45 (23.2) 97 (31.6) 177 (32.8)
Remission [n, %] 118 (61.5) 162 (52.8) 289 (53.1)
Others [n, %] 17 (8.9) 29 (9.7) 62 (11.6)
Patients demand [n, %] 79 (41.1) 134 (43.4) 231 (42.9)