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Table 2 Selected effectiveness parameters after three months, six months, 12 months, 18 months and 24 months

From: Outcome of children with oligoarticular juvenile idiopathic arthritis compared to polyarthritis on methotrexate- data of the German BIKER registry

 

Month 0

Month 3

Month 6

Month 12

Month 18

Month 24

Physician global assessment; median (IQR)

 persistent oligoJIA

40 (20; 63)

7 (2; 17)

3 (1; 13)

3(1;13.5)

3 (0; 13)

2 (0; 8)

 extended oligoJIA

45 (25; 65)

12 (4; 23)

8.5(2,5; 20,5)

3(1; 13.5)

3 (0; 13)

3 (0; 11)

 RF negative PA

54.5 (34; 79)

15 (5; 29)

9 (3; 20)

5 (1; 16)

3 (0; 10)

3 (0; 7)

parents/patient global assessment; median (IQR)

 persistent oligoJIA

35 (11; 55)

6 (2; 19)

4 (1; 13)

3 (0, 11)

2 (0, 9)

2 (0; 10)

 extended oligoJIA

36 (15; 55)

12(2; 29)

7 (2; 18)

5 (1,18)

3 (0; 17)

2 (0, 16)

 RF negative PA

44 (22; 63)

14 (4; 31)

8 (2; 22)

6 (1; 19)

3 (0; 19)

3 (0; 11)

CRP > 5; n (%)

 persistent oligoJIA

117 (33.7)

27 (13.6)

20 (11.1)

9 (5.4)

10 (6.6)

10 (8.1)

 extended oligoJIA

91 (45)

26 (20.6)

21 ((16.7)

17 (14.5)

12 (12.1)

11 (11.6)

 RF negative PA

217 (48.5)

53 (18.3)

53 (18.7)

44 (17.5)

22 (10.5)

18 (10.2)

  1. Data as observed. #Data are given as median and interquartile range (IQR) of patients on treatment as observed
  2. 100 mm scale was used to assess the patient’s and physician’s global assessment of disease activity (0 = best, 100 = worst) number of active joints (defined by the presence of swelling or, when absent, the limited range of motion accompanied by either pain or tenderness on motion)