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Table 2 Body composition, systemic inflammation and cardiometabolic risk factors between childhood-onset Takayasu Arteritis patients (c-TA) and healthy controls (CTRL).

From: Poor physical activity levels and cardiorespiratory fitness among patients with childhood-onset takayasu arteritis in remission: a cross‐sectional, multicenter study

Characteristics c-TA
(n = 17)
CRTL
(n = 17)
Between-group difference (95 % CI) P
DXA measurements
 BMD (L1-L4) (g/cm2) 0.89 ± 0.16 1.02 ± 0.16 -0.13 (-0.01 to -0.24) 0.025
 BMD total hip (g/cm2) 0.89 ± 0.17 0.99 ± 0.15 -0.10 (0.01 to -0.21) 0.080
 BMC total body (kg) 1.86 ± 0.48 2.28 ± 0.58 -0.42 (-0.04 to -0.79) 0.023
 BMD total body (kg) 1.03 ± 0.12 1.13 ± 0.13 -0.10 (-0.01 to -0.18) 0.032
 Lean mass + BMC (kg) 39.6 ± 9.03 49.0 ± 13.4 -9.40 (-1.41 to -17.3) 0.028
 Lean mass (kg) 37.9 ± 8.69 45.3 ± 11.2 -7.40 (-0.39 to -14.4) 0.029
 Percent fat mass (kg) 30.1 ± 8.30 23.2 ± 7.80 6.90 (1.27 to 12.5) 0.024
 Visceral fat (kg) 2.75 ± 1.30 2.14 ± 0.85 0.61 (-0.15 to 1.37) 0.201
Systemic inflammation
 C-reactive protein (mg/L) 4.84 ± 6.63 2.30 ± 1.64 2.54 (-0.83 to 5.91) 0.135
 ESR (mm/1st hour) 9.18 ± 9.22 4.89 ± 2.24 4.29 (-0.39 to 8.97) 0.072
 IFN-γ (mg/L) 7.70 ± 13.1 1.70 ± 0.90 6.00 (-0.48 to 12.4) 0.078
 IL-10 (pg/mL) 14.8 ± 16.0 7.70 ± 3.77 7.10 (-1.02 to 15.2) 0.081
 IL-12p70 (pg/mL) 5.46 ± 3.76 4.74 ± 1.90 0.72 (2.80 to -1.36) 0.488
 IL-1ra (pg/mL) 123.6 ± 236.3 34.4 ± 15.6 89.2 (-27.7 to 206.1) 0.126
 IL1-β (pg/mL) 2.55 ± 1.25 2.16 ± 0.40 0.39 (-0.25 to 1.03) 0.233
 IL-6 (pg/mL) 21.7 ± 32.3 15.2 ± 28.4 6.50 (-14.7 to 27.7) 0.542
 TNF-α (pg/mL) 15.1 ± 7.27 13.2 ± 6.60 1.90 (-2.95 to 6.75) 0.443
 VEGF (pg/mL) 2.86 ± 4.89 1.67 ± 0.60 1.19 (-1.24 to 3.62) 0.337
 PDGF (pg/mL) 561.4 ± 1273.8 766.1 ± 1529.3 -204.7 (778.2 to -1187.6) 0.667
Cardiometabolic risk factors
 SBP (mmHg) 110.9 ± 15.3 104.8 ± 8.1 6.10 (-2.45 to 14.6) 0.225
 DBP (mmHg) 64.4 ± 9.30 68.3 ± 8.20 -3.90 (2.23 to -10.0) 0.251
 Glucose fasting (mg/dL) 83.1 ± 8.70 82.2 ± 4.55 0.90 (-3.95 to 5.75) 0.723
 Insulin fasting (mg/dL) 13.9 ± 9.85 8.37 ± 3.80 5.53 (0.31 to 10.7) 0.050
 HOMA-IR 2.88 ± 2.11 1.67 ± 0.78 1.21 (0.09 to 2.32) 0.033
 Total cholesterol (mg/dL) 151.2 ± 19.5 156.2 ± 18.8 -5.00 (8.38 to -18.4) 0.479
 HDL cholesterol (mg/dL) 53.4 ± 13.6 66.1 ± 14.1 -12.7 (-3.02 to -22.3) 0.017
 LDL cholesterol (mg/dL) 82.0 ± 16.9 75.6 ± 13.4 6.40 (-4.25 to 17.0) 0.271
 VLDL cholesterol (mg/dL) 15.8 ± 2.98 14.6 ± 3.02 1.20 (-0.89 to 3.29) 0.262
 Triglycerides (mg/dL) 71.2 ± 25.1 60.5 ± 14.9 10.7 (-3.72 to 25.1) 0.139
  1. Values are means ± SD. DXA (dual-energy x-ray absorptiometry), BMD (bone mineral density), BMC (bone mineral content), ESR (erythrocyte sedimentation rate), IFN-γ (interferon gamma), IL-10 (interleukin 10), IL-12p70 (interleukin 12p70), IL-1ra (interleukin 1 receptor antagonist), IL-1β (interleukin 1 beta), IL-6 (interleukin 6), TNF-α (tumor necrosis factor alfa), VEGF (vascular endothelial growth factor), PDGF (platelet-derived growth factor), SBP (systolic blood pressure), DBP (diastolic blood pressure), HOMA-IR (homeostatic model assessment for insulin resistance), HDL (high-density lipoprotein), LDL (low-density lipoprotein), VLDL (very-low-density lipoprotein),
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