Skip to main content

Table 2 Body composition, systemic inflammation and cardiometabolic risk factors between childhood-onset Takayasu Arteritis patients (c-TA) and healthy controls (CTRL).

From: Poor physical activity levels and cardiorespiratory fitness among patients with childhood-onset takayasu arteritis in remission: a cross‐sectional, multicenter study

Characteristics

c-TA

(n = 17)

CRTL

(n = 17)

Between-group difference (95 % CI)

P

DXA measurements

 BMD (L1-L4) (g/cm2)

0.89 ± 0.16

1.02 ± 0.16

-0.13 (-0.01 to -0.24)

0.025

 BMD total hip (g/cm2)

0.89 ± 0.17

0.99 ± 0.15

-0.10 (0.01 to -0.21)

0.080

 BMC total body (kg)

1.86 ± 0.48

2.28 ± 0.58

-0.42 (-0.04 to -0.79)

0.023

 BMD total body (kg)

1.03 ± 0.12

1.13 ± 0.13

-0.10 (-0.01 to -0.18)

0.032

 Lean mass + BMC (kg)

39.6 ± 9.03

49.0 ± 13.4

-9.40 (-1.41 to -17.3)

0.028

 Lean mass (kg)

37.9 ± 8.69

45.3 ± 11.2

-7.40 (-0.39 to -14.4)

0.029

 Percent fat mass (kg)

30.1 ± 8.30

23.2 ± 7.80

6.90 (1.27 to 12.5)

0.024

 Visceral fat (kg)

2.75 ± 1.30

2.14 ± 0.85

0.61 (-0.15 to 1.37)

0.201

Systemic inflammation

 C-reactive protein (mg/L)

4.84 ± 6.63

2.30 ± 1.64

2.54 (-0.83 to 5.91)

0.135

 ESR (mm/1st hour)

9.18 ± 9.22

4.89 ± 2.24

4.29 (-0.39 to 8.97)

0.072

 IFN-γ (mg/L)

7.70 ± 13.1

1.70 ± 0.90

6.00 (-0.48 to 12.4)

0.078

 IL-10 (pg/mL)

14.8 ± 16.0

7.70 ± 3.77

7.10 (-1.02 to 15.2)

0.081

 IL-12p70 (pg/mL)

5.46 ± 3.76

4.74 ± 1.90

0.72 (2.80 to -1.36)

0.488

 IL-1ra (pg/mL)

123.6 ± 236.3

34.4 ± 15.6

89.2 (-27.7 to 206.1)

0.126

 IL1-β (pg/mL)

2.55 ± 1.25

2.16 ± 0.40

0.39 (-0.25 to 1.03)

0.233

 IL-6 (pg/mL)

21.7 ± 32.3

15.2 ± 28.4

6.50 (-14.7 to 27.7)

0.542

 TNF-α (pg/mL)

15.1 ± 7.27

13.2 ± 6.60

1.90 (-2.95 to 6.75)

0.443

 VEGF (pg/mL)

2.86 ± 4.89

1.67 ± 0.60

1.19 (-1.24 to 3.62)

0.337

 PDGF (pg/mL)

561.4 ± 1273.8

766.1 ± 1529.3

-204.7 (778.2 to -1187.6)

0.667

Cardiometabolic risk factors

 SBP (mmHg)

110.9 ± 15.3

104.8 ± 8.1

6.10 (-2.45 to 14.6)

0.225

 DBP (mmHg)

64.4 ± 9.30

68.3 ± 8.20

-3.90 (2.23 to -10.0)

0.251

 Glucose fasting (mg/dL)

83.1 ± 8.70

82.2 ± 4.55

0.90 (-3.95 to 5.75)

0.723

 Insulin fasting (mg/dL)

13.9 ± 9.85

8.37 ± 3.80

5.53 (0.31 to 10.7)

0.050

 HOMA-IR

2.88 ± 2.11

1.67 ± 0.78

1.21 (0.09 to 2.32)

0.033

 Total cholesterol (mg/dL)

151.2 ± 19.5

156.2 ± 18.8

-5.00 (8.38 to -18.4)

0.479

 HDL cholesterol (mg/dL)

53.4 ± 13.6

66.1 ± 14.1

-12.7 (-3.02 to -22.3)

0.017

 LDL cholesterol (mg/dL)

82.0 ± 16.9

75.6 ± 13.4

6.40 (-4.25 to 17.0)

0.271

 VLDL cholesterol (mg/dL)

15.8 ± 2.98

14.6 ± 3.02

1.20 (-0.89 to 3.29)

0.262

 Triglycerides (mg/dL)

71.2 ± 25.1

60.5 ± 14.9

10.7 (-3.72 to 25.1)

0.139

  1. Values are means ± SD. DXA (dual-energy x-ray absorptiometry), BMD (bone mineral density), BMC (bone mineral content), ESR (erythrocyte sedimentation rate), IFN-γ (interferon gamma), IL-10 (interleukin 10), IL-12p70 (interleukin 12p70), IL-1ra (interleukin 1 receptor antagonist), IL-1β (interleukin 1 beta), IL-6 (interleukin 6), TNF-α (tumor necrosis factor alfa), VEGF (vascular endothelial growth factor), PDGF (platelet-derived growth factor), SBP (systolic blood pressure), DBP (diastolic blood pressure), HOMA-IR (homeostatic model assessment for insulin resistance), HDL (high-density lipoprotein), LDL (low-density lipoprotein), VLDL (very-low-density lipoprotein),