Characteristics | c-TA (n = 17) | CRTL (n = 17) | Between-group difference (95 % CI) | P |
---|---|---|---|---|
DXA measurements | ||||
BMD (L1-L4) (g/cm2) | 0.89 ± 0.16 | 1.02 ± 0.16 | -0.13 (-0.01 to -0.24) | 0.025 |
BMD total hip (g/cm2) | 0.89 ± 0.17 | 0.99 ± 0.15 | -0.10 (0.01 to -0.21) | 0.080 |
BMC total body (kg) | 1.86 ± 0.48 | 2.28 ± 0.58 | -0.42 (-0.04 to -0.79) | 0.023 |
BMD total body (kg) | 1.03 ± 0.12 | 1.13 ± 0.13 | -0.10 (-0.01 to -0.18) | 0.032 |
Lean mass + BMC (kg) | 39.6 ± 9.03 | 49.0 ± 13.4 | -9.40 (-1.41 to -17.3) | 0.028 |
Lean mass (kg) | 37.9 ± 8.69 | 45.3 ± 11.2 | -7.40 (-0.39 to -14.4) | 0.029 |
Percent fat mass (kg) | 30.1 ± 8.30 | 23.2 ± 7.80 | 6.90 (1.27 to 12.5) | 0.024 |
Visceral fat (kg) | 2.75 ± 1.30 | 2.14 ± 0.85 | 0.61 (-0.15 to 1.37) | 0.201 |
Systemic inflammation | ||||
C-reactive protein (mg/L) | 4.84 ± 6.63 | 2.30 ± 1.64 | 2.54 (-0.83 to 5.91) | 0.135 |
ESR (mm/1st hour) | 9.18 ± 9.22 | 4.89 ± 2.24 | 4.29 (-0.39 to 8.97) | 0.072 |
IFN-γ (mg/L) | 7.70 ± 13.1 | 1.70 ± 0.90 | 6.00 (-0.48 to 12.4) | 0.078 |
IL-10 (pg/mL) | 14.8 ± 16.0 | 7.70 ± 3.77 | 7.10 (-1.02 to 15.2) | 0.081 |
IL-12p70 (pg/mL) | 5.46 ± 3.76 | 4.74 ± 1.90 | 0.72 (2.80 to -1.36) | 0.488 |
IL-1ra (pg/mL) | 123.6 ± 236.3 | 34.4 ± 15.6 | 89.2 (-27.7 to 206.1) | 0.126 |
IL1-β (pg/mL) | 2.55 ± 1.25 | 2.16 ± 0.40 | 0.39 (-0.25 to 1.03) | 0.233 |
IL-6 (pg/mL) | 21.7 ± 32.3 | 15.2 ± 28.4 | 6.50 (-14.7 to 27.7) | 0.542 |
TNF-α (pg/mL) | 15.1 ± 7.27 | 13.2 ± 6.60 | 1.90 (-2.95 to 6.75) | 0.443 |
VEGF (pg/mL) | 2.86 ± 4.89 | 1.67 ± 0.60 | 1.19 (-1.24 to 3.62) | 0.337 |
PDGF (pg/mL) | 561.4 ± 1273.8 | 766.1 ± 1529.3 | -204.7 (778.2 to -1187.6) | 0.667 |
Cardiometabolic risk factors | ||||
SBP (mmHg) | 110.9 ± 15.3 | 104.8 ± 8.1 | 6.10 (-2.45 to 14.6) | 0.225 |
DBP (mmHg) | 64.4 ± 9.30 | 68.3 ± 8.20 | -3.90 (2.23 to -10.0) | 0.251 |
Glucose fasting (mg/dL) | 83.1 ± 8.70 | 82.2 ± 4.55 | 0.90 (-3.95 to 5.75) | 0.723 |
Insulin fasting (mg/dL) | 13.9 ± 9.85 | 8.37 ± 3.80 | 5.53 (0.31 to 10.7) | 0.050 |
HOMA-IR | 2.88 ± 2.11 | 1.67 ± 0.78 | 1.21 (0.09 to 2.32) | 0.033 |
Total cholesterol (mg/dL) | 151.2 ± 19.5 | 156.2 ± 18.8 | -5.00 (8.38 to -18.4) | 0.479 |
HDL cholesterol (mg/dL) | 53.4 ± 13.6 | 66.1 ± 14.1 | -12.7 (-3.02 to -22.3) | 0.017 |
LDL cholesterol (mg/dL) | 82.0 ± 16.9 | 75.6 ± 13.4 | 6.40 (-4.25 to 17.0) | 0.271 |
VLDL cholesterol (mg/dL) | 15.8 ± 2.98 | 14.6 ± 3.02 | 1.20 (-0.89 to 3.29) | 0.262 |
Triglycerides (mg/dL) | 71.2 ± 25.1 | 60.5 ± 14.9 | 10.7 (-3.72 to 25.1) | 0.139 |