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Fig. 1 | Pediatric Rheumatology

Fig. 1

From: Predictive value of C-reactive protein to albumin ratio as a biomarker for initial and repeated intravenous immunoglobulin resistance in a large cohort of Kawasaki disease patients: a prospective cohort study

Fig. 1

The flowchart of our prospective cohort study. In total, 763 patients were diagnosed with KD on admission. Those who had received IVIG treatment in other medical facilities (n = 126) or did not receive IVIG treatment before 10 days from fever onset (n = 38) were firstly excluded. Another 30 patients were also excluded due to lack of data regarding complete blood count (CBC) or CRP (n = 18) or serum ALB (n = 12) before initial IVIG. Additionally, we excluded 19 patients because other laboratory data (n = 10) or follow-up results (n = 9) were incomplete. Finally, 550 patients were enrolled for analysis, including 471 of initial IVIG responders and 79 of initial IVIG non-responders. Of the 79 patients with initial IVIG resistance, 31 of them did not respond to repeated IVIG treatment and received pulse intravenous methylprednisolone infusion

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