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Table 3 Predictors of abnormal brain magnetic resonance imaging (MRI) in patients with Parry-Romberg (PRS) and en coup de sabre (ECDS)

From: Magnetic resonance imaging findings in children with Parry-Romberg syndrome and en coup de sabre

 

Normal MRI

Abnormal MRI

p

Patient demographics

Disease

ECDS

4

2

0.59

ECDS/PRS

3

5

Sex

M

4

2

0.59

F

3

5

Additional clinical features

Any

Any

Yes

5

7

0.46

No

2

0

Neurological

Any

Yes

3

6

0.27

No

4

1

Seizures

Yes

1

5

0.1

No

6

2

Headaches

Yes

2

2

1

No

5

5

Cranial nerve dysfunction

Yes

0

2

0.46

No

7

5

Transient ischaemic attack

Yes

0

1

1

No

7

6

Myoclonus

Yes

0

1

1

No

7

6

Hyperaesthesia

Yes

1

0

1

No

6

7

Gait disturbance

Yes

0

1

1

No

7

6

Psychiatric disorder(s)

Any

Yes

2

2

1

No

5

5

Anxiety

Yes

1

1

1

No

6

6

Depression

Yes

0

1

1

No

7

6

OCD

Yes

0

1

1

No

7

6

Visual hallucinations

Yes

1

0

1

No

6

7

Cardiovascular

Any

Yes

1

1

1

No

6

6

Hypertension

Yes

0

1

1

No

7

6

Bicuspid aortic valve

Yes

1

0

1

No

6

7

Articular

TMJ dysfunction

Yes

1

0

1

No

6

7

Muscular

Myositis

Yes

1

0

1

No

6

7

Laboratory and other investigations

Autoantibodies

ANA

Yes

3

4

1

No

3

2

Anti-smooth muscle

Yes

0

1

0.4

No

3

1

RF

Yes

0

1

0.33

No

4

1

ENA

Yes

0

0

1

No

1

5

dsDNA

Yes

0

0

1

No

3

4

Cerebrospinal fluid

Inflammatory infiltrate

Yes

0

0

1

No

0

3

Neurophysiology

EEG abnormality

Yes

1

3

1

No

0

1

  1. OCD obsessive compulsive disorder, TMJ temporomandibular joint, ANA antinuclear antibody, RF rheumatoid factor, ENA extractable nuclear antigens, dsDNA double stranded DNA, EEG electroencephalography