Table 2 Inflammation parameters before and during IL-1i, p value for test of change between inflammation parameters before and during treatment with ANA / CANA
Before treatment | During treatment | p-value | ||
|---|---|---|---|---|
Leukocytes /nl | Leukocytes /nl | |||
ANA n = 51 | 14.6 (3.5–49.0) | ANA n = 79 | 8.8. (2.4–21.8) | < 0.001 |
CANA n = 21 | 11.0 (5.4–28.3) | CANA n = 24 | 7.2 (4.9–15.4) | < 0.001 |
CRP mg/l | CRP mg/l | |||
ANA n = 51 | 48.7 (0–531) | ANA n = 78 | 17.1 (0–178.4) | < 0.001 |
CANA n = 20 | 16.3 (0–178.3) | CANA n = 26 | 6.4 (0–100) | 0.014 |
ESR (after 1 h) mm/h | ESR (after 1 h) mm/h | |||
ANA n = 48 | 44.5 (1–106) | ANA n = 75 | 18 (1–125) | < 0.001 |
CANA n = 18 | 28.3 (7–100) | CANA n = 20 | 8.6 (1–101) | 0.004 |
SAA mg/l | SAA mg/l | |||
ANA n = 9 | 357 (9.1–1510) | ANA n = 33 | 25.6 (0–1840) | 0.014 |
CANA n = 6 | 26.4 (0.7–1840) | CANA n = 4 | 10.4 (0.5–1050) | 0.663 |
S100A12 ng/ml | S100A12 ng/ml | |||
ANA n = 14 | 5740 (300–60,630) | ANA n = 51 | 220 (5–58,643) | 0.021 |
CANA n = 14 | 2709 (0–60,630) | CANA n = 18 | 125 (0–5690) | 0.001 |