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Table 2 Inflammation parameters before and during IL-1i, p value for test of change between inflammation parameters before and during treatment with ANA / CANA

From: Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis – data from the German AID-registry

  Before treatment During treatment p-value
Leukocytes /nl   Leukocytes /nl   
 ANA n = 51 14.6 (3.5–49.0) ANA n = 79 8.8. (2.4–21.8) < 0.001
 CANA n = 21 11.0 (5.4–28.3) CANA n = 24 7.2 (4.9–15.4) < 0.001
CRP mg/l   CRP mg/l   
 ANA n = 51 48.7 (0–531) ANA n = 78 17.1 (0–178.4) < 0.001
 CANA n = 20 16.3 (0–178.3) CANA n = 26 6.4 (0–100) 0.014
ESR (after 1 h) mm/h   ESR (after 1 h) mm/h   
 ANA n = 48 44.5 (1–106) ANA n = 75 18 (1–125) < 0.001
 CANA n = 18 28.3 (7–100) CANA n = 20 8.6 (1–101) 0.004
SAA mg/l   SAA mg/l   
 ANA n = 9 357 (9.1–1510) ANA n = 33 25.6 (0–1840) 0.014
 CANA n = 6 26.4 (0.7–1840) CANA n = 4 10.4 (0.5–1050) 0.663
S100A12 ng/ml   S100A12 ng/ml   
 ANA n = 14 5740 (300–60,630) ANA n = 51 220 (5–58,643) 0.021
 CANA n = 14 2709 (0–60,630) CANA n = 18 125 (0–5690) 0.001