Skip to main content

Table 1 Patient characteristics and disease courses

From: Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis – data from the German AID-registry

 

ANA n = 84

CANA n = 27

 

ANA n = 80a

CANA n = 26a

Age at diagnosis

5.5 years

7.4 years

   

Symptoms before IL-1i

  

under IL-1i

  

Fever

90%

85%

 

28%

27%

Skin involvement

71%

81%

 

25%

33%

- Joint involvement* (arthritis/arthralgia)

59 70% / 19 23%

23 85% / 16 59%

 

37 46% / 21 26%

11 41% / 5 19%

- Abdominal

30%

70%

 

13%

26%

- Serositis

17%

11%

 

4%

4%

Duration of initial therapy to IL-1i

15 months

15 months

   

Age at start of IL-1i

6.8 years

8.7 years

   

Duration of IL-1i

34 months

16 months

   

Disease course

 MC

7 (8%)

0 (0%)

   

 PC

36 (43%)

14 (52%)

   

 PA

41 (49%)

13 (48%)

   

Joint involvement*

polyarthritis 41 (49%)

13 (48%)

 

25 (31%)

7 (27%)

oligoarthritis 18 (21%)

8 (30%)

 

12 (15%)

4 (15%)

arthralgia 19 (23%)

16 (59%)

 

21 (26%)

5 (19%)

none 6 (7%)

0 (0%)

 

22 (28%)

10 (38%)

  1. asymptoms unsatisfactory recorded
  2. (IL-1i IL-1 inhibition, MC monocyclic, PC polycyclic, PA polyarticular)
  3. *Specification of joint involvement