Skip to main content

Table 3 Laboratory and echocardiography results

From: Distinguishing active pediatric COVID-19 pneumonia from MIS-C

 

Active COVID-19 Pneumonia (N = 16)

Moderate COVID-19 Pneumonia (N = 8)

Severe COVID-19 Pneumonia (N = 8)

MIS-C (N = 21)

Mild MIS-C (N = 10)

Severe MIS-C (N = 11)

Total vs Total

Severe vs Severe

Laboratory findings on admission - no. (%)

 Acute kidney injury

5 (31)

3 (37.5)

2 (25)

8 (38)

2 (20)

6 (55)

0.7386

0.3521

 Elevated liver enzymes

12 (75)

7 (87.5)

5 (62.5)

13 (62)

5 (50)

8 (73)

0.4912

1.0000

 Lymphopenia

9 (56)

4 (50)

5 (62.5)

14 (67)

6 (60)

8 (73)

0.7332

1.0000

 Thrombocytopenia

3 (19)

0 (0)

3 (37.5)

5 (24)

1 (10)

4 (36)

1.0000

1.0000

Laboratory values on admission - median value (IQR)

 Sodium (mmoL/L)

139 (136.75–141.25)

137.5 (135.75–138.25)

141.5 (139.75–142.25)

133 (131.75–134.25)

134 (133–136.5)

132 (130.3–133)

0.0004

0.0059

 Creatinine (mg/dL)

0.78 (0.52–1.14)

0.73 (0.56–0.99)

0.78 (0.38–1.39)

0.79 (0.59–0.89)

0.6 (0.57–0.76)

0.83 (0.77–1.24)

0.9390

0.5357

 Albumin (g/dL)

3.7 (3.25–4.15)

4 (3.7–4.3)

3.3 (3.05–3.7)

3.4 (3–3.6)

3.6 (3.25–3.68)

3 (2.6–3.5)

0.0821

0.2898

 Alanine transaminase (U/L)

37.4 (18.8–58.05)

55.05 (23.33–153.13)

28.55 (16.4–44.03)

42.4 (20.9–65.35)

34.3 (15.2–52.8)

52.2 (27.73–73.6)

0.9746

0.1309

 Aspartate transaminase (U/L)

54.5 (33.75–115.25)

60.5 (48–126.25)

44.5 (27.25–70.25)

43 (25.75–56.25)

34 (24.25–46)

43.5 (36.25–56.75)

0.2791

0.6251

 Brain znatriuretic peptide (pg/mL)

46.85 (27.25–111.375)

10 (10–31.7)

101.4 (39.85–1281.85)

642.5 (47.1–1129.15)

40.75 (10–101.6)

1004.95 (229.5–1778.5)

0.7353

0.6184

 Troponin (ng/mL)

0.01 (0.01–0.02)

0.01 (0.01–0.02)

0.02 (0.01–0.05)

0.1 (0.02–1.4)

0.01 (0.01–0.07)

0.24 (0.03–2.17)

0.3194

0.2689

 C-reactive protein (mg/dL)

4.6 (1.41–11.11)

3.62 (1.27–4.95)

9.2 (1.43–11.9)

15.93 (11.17–23.1)

14 (6.21–18.14)

17.73 (11.98–27.62)

0.0015

0.0057

 Erythrocyte sedimentation rate (mm/hr)

25 (9–40)

29.5 (13–38.5)

19 (12.5–35)

48 (38–58)

49.5 (40.75–59.25)

41 (38–58)

0.0031

0.0097

 Procalcitonin (ng/mL)

0.77 (0.37–2.65)

0.37 (0.18–3.28)

1.32 (0.77–2.61)

11.51 (4.35–24.41)

2.18 (1.90–2.45)

13.51 (8.41–31.96)

0.0004

0.0013

 White blood cell count (10^3/uL)

9.95 (4.54–13.85)

4.3 (2.39–7.39)

11.44 (9.74–22.61)

10.58 (8.44–12.78)

10.82 (8.1–11.84)

9.79 (8.88–14.92)

0.4903

0.3218

 Absolute lymphocyte count (10^3/uL)

1.15 (0.59–1.42)

1.15 (0.53–1.32)

1.19 (0.83–1.51)

0.84 (0.5–1.51)

1.07 (0.91–1.75)

0.5 (0.44–0.74)

0.5774

0.1200

 Hemoglobin (g/dL)

12.1 (10.6–14.73)

12.6 (11.35–14.78)

11.7 (10.58–14.13)

11.5 (10.4–11.9)

11.55 (10.8–12.13)

11.3 (10.1–11.8)

0.1010

0.3020

 Platelet count (10^3/uL)

201 (164.75–263.5)

226.5 (181.25–276)

180.5 (77.25–239.5)

190 (155–225)

215 (165.75–271.3)

180 (129.5–201)

0.6567

0.9671

 International normalized ratio

1.1 (1.1–1.25)

1.13 (1.08–1.17)

1.1 (1.1–1.35)

1.24 (1.18–1.4)

1.15 (1.1–1.2)

1.4 (1.22–1.4)

0.0842

0.0877

 Ferritin (ng/mL)

472.6 (230.6–1982)

472.6 (230.6–683.4)

710.5 (246.55–1998.25)

520.1 (282.5–789.1)

461.9 (201.25–761.9)

520.1 (370.7–1032.5)

0.7632

0.9342

 Lactate dehydrogenase (U/L)

667 (462–818)

767 (609.5–4861.5)

647 (503.25–780.25)

244 (200–299)

271.5 (216–454.8)

225 (184.5–264)

0.0005

0.0049

 D-dimer FEU (ug/mL)

1.31 (0.61–1.94)

1.18 (0.65–1.29)

1.93 (1.21–2.03)

2.51 (1.58–3.25)

1.71 (1.37–2.35)

3.15 (2.42–3.79)

0.0236

0.0416

 Fibrinogen (mg/dL)

447 (312.5–594)

529 (513–610)

373 (260.25–500)

544 (467–632)

561.5 (424.75–633.3)

489 (468.5–629)

0.2114

0.0987

Echocardiography findings - no./total no. (%)

 Decreased systolic function or ejection fraction

1/7 (14)

0/2 (0)

1/5 (20)

5/21 (24)

1/10 (10)

4/11 (36)

1.0000

0.6000

 Coronary artery dilation

0/7 (0)

0/2 (0)

0/5 (0)

7/21 (33)

2/10 (20)

5/11 (45)

0.1414

0.1186

 Z-score - median value (IQR)

N/A

N/A

N/A

2.15 (2.12–2.92)

2.12 (2.11–2.12)

2.81 (2.15–3.03)

N/A

N/A

 Heart block

0/7 (0)

0/2 (0)

0/5 (0)

1/21 (5)

0/10 (0)

1/11 (9)

1.0000

1.0000