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Fig. 4 | Pediatric Rheumatology

Fig. 4

From: A novel mutation in early‐onset sarcoidosis/Blau syndrome: an association with Propionibacterium acnes

Fig. 4

P. acnes detected by PAB antibody within the sarcoid granulomas of biopsied skin lesion. Hematoxylin and eosin stain and IHC with PAB antibody and LAM antibody as control are shown pairwise. a Noncaseating epithelioid cell granulomas in the dermis. b Higher magnification of the granuloma indicated by an arrow in (a). c No positive signal detected by LAM antibody in the identical granuloma. d Many round bodies detected by PAB antibody in the granuloma (arrows). Scale bar; 50 µm.

IHC, immunohistochemistry; PAB, Propionibacterium acnes-specific monoclonal; LAM, mycobacteria-specific monoclonal

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Pediatric Rheumatology

ISSN: 1546-0096