Integrin α2 gene polymorphism is a risk factor of coronary artery lesions in Chinese children with Kawasaki disease

Table 3 Stratification analysis of rs1126643 polymorphism in KD cases with the CAL and NCAL

Variables	rs1126643 (Cases/Controls)		P-value^a	OR (95% CI)	P-value	Adjusted OR (95% CI)	Adjusted P-value^b
Variables	CC	CT/TT	P-value^a	OR (95% CI)	P-value	Adjusted OR (95% CI)	Adjusted P-value^b
Age, months
≤ 60	126/238	145/187	0.0143	1.47 (1.08–1.99)	0.0145	1.44 (1.06–1.96)	0.0199
> 60	12/35	17/25	0.1328	1.98 (0.81–4.88)	0.1358	2.02 (0.82–4.99)	0.1292
sex
Male	97/176	123/149	0.0210	1.50 (1.06–2.11)	0.0214	1.50 (1.06–2.11)	0.0218
Female	41/97	39/63	0.1670	1.47 (0.85–2.52)	0.1669	1.52 (0.88–2.61)	0.1357
Severity of CAL
SCAL^c	86/273	102/212	0.0139	1.53 (1.09–2.14)	0.0142	1.47 (1.04–2.08)	0.0277
MCAL^d	27/273	36/212	0.0444	1.72 (1.01–2.92)	0.0457	1.72 (1.01–2.93)	0.0451
GCAL^e	25/273	24/212	0.4803	1.24 (0.69–2.23)	0.4797	1.23 (0.68–2.22)	0.4992

^a Two-sided χ2 test for distributions between Kawasaki disease patients with the CAL and NCAL. ^b Adjusted for sex/age status in logistic regress models. ^c Kawasaki disease patients with coronary artery dilatations/small aneurysms. ^d Kawasaki disease patients with coronary artery medium aneurysms. ^e Kawasaki disease patients with coronary artery giant aneurysms

ISSN: 1546-0096