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Table 3 Serum levels of CaN and NFAT1 in Kawasaki disease with or without coronary artery lesions

From: The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease

Characteristics

stage

KD with CALs(n = 9)

KD without CALs(n = 65)

p value

Boys/girls

 

7/2

45/20

0.716

CaN (ng/ml)

Acute stage

3.13 ± 0.52

2.95 ± 0.65

0.444

Afebrile stage

2.77 ± 0.46

2.70 ± 0.58

0.743

Subacute stage

2.50 ± 0.44

2.45 ± 0.50*▲▲

0.226

NFAT1(pg/ml)

Acute stage

297.46 ± 13.84

306.75 ± 30.73

0.135

Afebrile stage

268.82 ± 11.96▲▲

285.84 ± 25.13▲▲

0.003

Subacute stage

250.43 ± 20.15*▲▲

261.00 ± 24.81**▲▲

0.226

IL-2(pg/ml)

Acute stage

3.83 ± 1.28

4.20 ± 1.28

0.442

IL-4(pg/ml)

Acute stage

3.5 ± 1.15

5.61 ± 5.33

0.013

IL-6(pg/ml)

Acute stage

35.19 ± 29.14

107.8 ± 148.28

0.002

IL-10(pg/ml)

Acute stage

8.30 ± 6.99

19.36 ± 22.21

0.006

  1. P < 0.05, ▲▲P < 0.01 compared with patients at acute stage
  2. *P < 0.05, **P < 0.01 compared with patients at afebrile stage