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Table 3 Serum levels of CaN and NFAT1 in Kawasaki disease with or without coronary artery lesions

From: The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease

CharacteristicsstageKD with CALs(n = 9)KD without CALs(n = 65)p value
Boys/girls 7/245/200.716
CaN (ng/ml)Acute stage3.13 ± 0.522.95 ± 0.650.444
Afebrile stage2.77 ± 0.462.70 ± 0.580.743
Subacute stage2.50 ± 0.442.45 ± 0.50*▲▲0.226
NFAT1(pg/ml)Acute stage297.46 ± 13.84306.75 ± 30.730.135
Afebrile stage268.82 ± 11.96▲▲285.84 ± 25.13▲▲0.003
Subacute stage250.43 ± 20.15*▲▲261.00 ± 24.81**▲▲0.226
IL-2(pg/ml)Acute stage3.83 ± 1.284.20 ± 1.280.442
IL-4(pg/ml)Acute stage3.5 ± 1.155.61 ± 5.330.013
IL-6(pg/ml)Acute stage35.19 ± 29.14107.8 ± 148.280.002
IL-10(pg/ml)Acute stage8.30 ± 6.9919.36 ± 22.210.006
  1. P < 0.05, ▲▲P < 0.01 compared with patients at acute stage
  2. *P < 0.05, **P < 0.01 compared with patients at afebrile stage